Time Course of Changes in Simulated Keratometry and Total Corneal Refractive Power after Corneal Collagen Cross-Linking for Progressive Keratoconus

BioMed Research International
Masahide TakahashiNobuyuki Shoji

Abstract

To assess the simulated keratometry (Sim K) and the total corneal refractive power (TCRP) in eyes undergoing conventional corneal cross-linking (CXL). This study comprised 20 eyes of 20 keratoconic patients (14 men and 6 women; median age (25th and 75th percentile), 26.5 (21.8, 38.0) years) who underwent CXL. The Sim K and TCRP were measured with a rotating Scheimpflug system (Pentacam HR, Oculus), preoperatively and 1, 3, 6, and 12 months postoperatively. The values of Sim K were 52.65 (46.00, 55.70), 52.45 (45.85, 56.88), 51.70 (45.78, 55.83), 51.40 (45.68, 56.80), and 51.25 (46.08, 56.15) D preoperatively and 1, 3, 6, and 12 months postoperatively, respectively. The corresponding figures of TCRP were 52.10 (45.48, 55.08), 51.30 (45.18, 55.20), 50.95 (45.15, 54.50), 50.00 (45.18, 55.08), and 49.80 (45.48, 54.15) D, respectively. The variances of the Sim K and TCRP data were not statistically significant (p=0.994 and p=0.970, respectively, Kruskal-Wallis test). The Sim K was significantly larger than the TCRP before CXL and at 1, 3, 6, and 12 months after CXL (p<0.001, Wilcoxon signed-rank test). Not only the Sim K but also TCRP was decreased by approximately 1 D after CXL. The Sim K readings may overestimate the TCRP, even af...Continue Reading

References

Mar 11, 1998·Survey of Ophthalmology·Y S Rabinowitz
Apr 30, 2003·American Journal of Ophthalmology·Gregor WollensakTheo Seiler
Jun 13, 2006·Journal of Cataract and Refractive Surgery·Antonio Leccisotti
Aug 11, 2006·Current Opinion in Ophthalmology·Gregor Wollensak
Sep 29, 2009·American Journal of Ophthalmology·Muriël DoorsRudy M M A Nuijts
Oct 14, 2009·Archives of Ophthalmology·Paolo VinciguerraDaniel Epstein
Dec 12, 2012·Journal of Cataract and Refractive Surgery·Raúl MontalbánDavid P Piñero
Aug 24, 2013·The British Journal of Ophthalmology·Martin P WatsonStephen J Tuft
Apr 1, 2014·Journal of Cataract and Refractive Surgery·Jagadesh C ReddyKristin M Hammersmith
Aug 25, 2015·American Journal of Ophthalmology·Kazutaka KamiyaToshiyuki Miyake

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