Abstract
Posttraumatic stress disorder (PTSD) often co-occurs with panic disorder (PD), with some etiological models positing a causal role of panic reactivity in PTSD onset; however, data addressing the temporal ordering of these conditions are lacking. The aim of this study was to examine the bi-directional associations between PD and PTSD in a nationally representative, epidemiologic sample of trauma-exposed adults. Participants were community-dwelling adults (62.6% women; Mage = 48.9, SD 16.3) with lifetime DSM-IV PTSD criterion A trauma exposure drawn from the 2001/2 National Epidemiologic Survey on Alcohol and Related Conditions (NESARC) and re-interviewed in 2004/5 (N = 12,467). Cox discrete-time proportional hazards models with time-varying covariates were used to investigate the bi-directional associations between lifetime PD and PTSD, accounting for demographic characteristics, trauma load, and lifetime history of major depression, generalized anxiety disorder, and social anxiety disorder. PD was significantly associated with subsequent onset of PTSD (HR 1.210, 95%CI = 1.207-1.214, p < .001), and PTSD was significantly associated with onset of PD (HR 1.601, 95% CI 1.597-1.604, p < .001). The association between PTSD and subseq...Continue Reading
References
Dec 1, 1995·Archives of General Psychiatry·R C KesslerC B Nelson
Nov 21, 1997·Archives of General Psychiatry·N BreslauL R Schultz
Feb 16, 2000·Acta Psychiatrica Scandinavica·A PerkoniggH U Wittchen
Mar 23, 2001·Journal of Abnormal Psychology·T A BrownL A Campbell
Sep 11, 2001·Psychiatry Research·S I ChantarujikapongW R True
Mar 29, 2002·The New England Journal of Medicine·Sandro GaleaDavid Vlahov
Oct 31, 2002·Journal of Anxiety Disorders·Gregory A Leskin, Javaid I Sheikh
Jul 12, 2003·Twin Research : the Official Journal of the International Society for Twin Studies·Karestan C KoenenMing T Tsuang
Aug 20, 2003·Journal of Consulting and Clinical Psychology·Dean G KilpatrickConnie L Best
Dec 1, 2004·The American Journal of Psychiatry·Renee D GoodwinHans-Ulrich Wittchen
Aug 8, 2006·Journal of Anxiety Disorders·Norman B SchmidtJ Anthony Richey
Aug 21, 2007·Drug and Alcohol Dependence·W June RuanBridget F Grant
May 13, 2008·Cognitive Behaviour Therapy·Devon E HintonDavid H Barlow
Jan 13, 2009·Depression and Anxiety·Carlos Israel Pérez BenítezMartin B Keller
Mar 27, 2009·Behaviour Research and Therapy·Timothy A Brown, Judiann McNiff
May 21, 2009·Journal of Traumatic Stress·Ananda B AmstadterSandro Galea
Aug 4, 2009·The British Journal of Psychiatry : the Journal of Mental Science·Alexander C McFarlane, Miranda Van Hooff
Feb 10, 2010·Journal of Abnormal Psychology·Grant N MarshallSherry H Stewart
May 12, 2010·Journal of Abnormal Psychology·Erika J WolfKarestan C Koenen
Mar 1, 2009·International Perspectives in Victimology·Ron AciernoSandro Galea
Jun 23, 2010·Psychological Bulletin·Teresa M LeyroAmit Bernstein
Sep 18, 2010·Journal of Traumatic Stress·Erin C Marshall-BerenzMichael J Zvolensky
Dec 21, 2010·Journal of Anxiety Disorders·Robert H PietrzakBridget F Grant
Feb 18, 2011·Journal of Psychiatric Research·Christoph MuhtzMichael Kellner
Feb 26, 2011·Journal of Traumatic Stress·Richard E Adams, Joseph A Boscarino
Mar 29, 2011·Journal of Psychiatric Research·Carmen P McLeanStefan G Hofmann
Aug 5, 2011·Journal of Traumatic Stress·Marie-Louise MeewisseBerthold P R Gersons
Oct 24, 2013·Journal of Traumatic Stress·Dean G KilpatrickMatthew J Friedman
Jun 18, 2017·Psychoneuroendocrinology·Susann WichmannKatja Petrowski
Citations
Feb 11, 2021·Family & Community Health·Rachel TamblingMorica Hutchison
May 14, 2021·Journal of Psychosomatic Research·Min MaXiquan Ma
Jul 3, 2021·Healthcare·Irina GeorgievaTella Lantta
Oct 3, 2021·Preventive Medicine·Kelly R PeckStacey C Sigmon
Sep 2, 2021·Applied Psychophysiology and Biofeedback·Michael J OstacherTrisha Suppes
Dec 30, 2021·Journal of Dual Diagnosis·Shannon M BlakeyTracy L Simpson