Time-course response in serum markers of bone turnover to a single-bout of electrical stimulation in patients with recent spinal cord injury.

European Journal of Applied Physiology
Alfredo Arija-BlázquezJosé Florensa-Vila

Abstract

The objective of the present repeat-measures study was to determine whether plasma serum levels of testosterone, cortisol, osteocalcin or type I collagen C-telopeptide (CT) are acutely affected following an electro-myostimulation (EMS) bout, and their relation to bone mineral density and muscle mass. Ten men with recent (8 weeks) thoracic spinal cord injury (SCI) (ASIA A) and 10 age-matched able-bodied (AB) men performed one EMS bout on the quadriceps femoris muscle. Blood samples were drawn at basal condition, immediately after EMS, and 15 min, 30 min, 24 h and 48 h post-EMS. Muscle cross-sectional area was measured by magnetic resonance imaging. Bone mineral density (BMD) was determined by dual-energy X-ray absorptiometry. In the SCI group, a significant decrease in testosterone, cortisol and CT together with a significant increase in testosterone/cortisol ratio and osteocalcin/CT ratio was observed after EMS. For the AB subjects, only testosterone and CT decreased significantly following EMS. Muscle size was only related to testosterone/cortisol ratio in the SCI sample (R = 0.659, p < 0.05), whereas BMD did not show any relation to any biomarker. Acute EMS in recent spinal cord injured men seems to induce positive effects on...Continue Reading

References

Feb 1, 1979·Urology·S D MadduriJ J Seebode
Feb 19, 1998·The Journal of Clinical Endocrinology and Metabolism·D RobertsP E Hickman
Oct 13, 1998·The Journal of Clinical Endocrinology and Metabolism·S M SmithC S Leach
Jan 14, 1999·Journal of Applied Physiology·M J CastroG A Dudley
Sep 14, 1999·European Journal of Applied Physiology and Occupational Physiology·M J CastroG A Dudley
Jan 4, 2001·European Journal of Applied Physiology·R M CrameriJ R Sutton
Jul 28, 2001·Medicine and Science in Sports and Exercise·T MohrM Kjaer
Oct 18, 2002·Scandinavian Journal of Medicine & Science in Sports·R M CrameriJ R Sutton
Dec 24, 2002·Prostate Cancer and Prostatic Diseases·E A BenaimC G Roehrborn
Feb 13, 2003·Clinical Endocrinology·A R Naderi, M R Safarinejad
Apr 26, 2003·European Journal of Clinical Investigation·P EserE Stüssi
Jul 12, 2003·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·Aubrey BlumsohnRichard Eastell
Aug 9, 2003·International Journal of Sports Medicine·J P AhtiainenK Häkkinen
Dec 25, 2003·Muscle & Nerve·Regina M CrameriAdele Weston
Apr 8, 2004·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·Julie A PascoGeoffrey C Nicholson
Jan 13, 2006·Journal of Neurophysiology·Richard K Shields, Shauna Dudley-Javoroski
Jan 19, 2006·American Journal of Physiology. Endocrinology and Metabolism·William A BaumanErnest Schwartz
Jun 14, 2006·Applied Physiology, Nutrition, and Metabolism = Physiologie Appliquée, Nutrition Et Métabolisme·Lora M GiangregorioNeil McCartney
Feb 6, 2007·The Journal of Spinal Cord Medicine·Lora Giangregorio, Neil McCartney
Aug 9, 2007·The Journal of Clinical Endocrinology and Metabolism·Donald J BrambillaJohn B McKinlay
Jan 19, 2008·Physical Therapy·Shauna Dudley-Javoroski, Richard K Shields
Feb 27, 2008·European Journal of Endocrinology·A SartorioN A Maffiuletti
Apr 29, 2008·Journal of Electromyography and Kinesiology : Official Journal of the International Society of Electrophysiological Kinesiology·L GriffinJ L Ivy
Nov 22, 2008·Journal of Applied Physiology·L WielopolskiW A Bauman
Apr 7, 2010·European Journal of Applied Physiology·Noortje van DuijnhovenMaria Hopman
Dec 15, 2010·PM & R : the Journal of Injury, Function, and Rehabilitation·Suzanne L GroahInger Ljungberg

❮ Previous
Next ❯

Citations

Sep 18, 2012·Current Osteoporosis Reports·Ricardo A BattaglinoLeslie R Morse
May 28, 2014·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·H M BramlettW Qin
Oct 5, 2013·The Journal of Spinal Cord Medicine·Alfredo Arija-BlázquezJosé Florensa-Vila
May 13, 2017·European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·Saeed Soleyman-JahiVafa Rahimi-Movaghar
Sep 11, 2019·Journal of Clinical Densitometry : the Official Journal of the International Society for Clinical Densitometry·Leslie R MorseBeverley C Craven
Apr 4, 2021·International Journal of Molecular Sciences·Ramsha ShamsNarendra L Banik

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.