Time delay of monitors of the hypnotic component of anesthesia: analysis of state entropy and index of consciousness

Anesthesia and Analgesia
Matthias KreuzerGerhard Schneider

Abstract

Monitors evaluating the hypnotic component of anesthesia by analyzing the electroencephalogram (EEG) may help to decrease the incidence of intraoperative awareness with recall. To calculate an index representing the anesthetic level, these monitors have different time delays until the correct index is displayed. In previous studies, intraoperatively recorded real and simulated EEG signals were used to determine time delays of cerebral state and Narcotrend and Bispectral indices. In the present study, we determined time delays of state entropy and index of consciousness. For this purpose, recorded real and simulated EEG sequences representing different anesthetic levels were played back to the tested monitors. Simulated and real perioperatively recorded EEG signals indicating stable states "awake," "general anesthesia," and "cortical suppression" were used to evaluate the time delays. Time delays were measured when switching from one state to another and were defined as the required time span of the monitor to reach the stable target index. Comparable results were obtained using simulated and real EEG sequences. Time delays were not constant and ranged from 18 to 152 seconds. They were also different for increasing and decreasin...Continue Reading

Citations

Jan 22, 2013·Canadian Journal of Anaesthesia = Journal Canadien D'anesthésie·François Moreau-BussièreEtienne de Médicis
Jan 21, 2014·Journal of Clinical Monitoring and Computing·Matthias KreuzerDenis Jordan
May 31, 2015·British Journal of Anaesthesia·S Pilge, G Schneider
Jun 14, 2013·Plant Signaling & Behavior·John Gardiner
Jan 15, 2014·Clinical EEG and Neuroscience·Nicolas MarchantVincent Bonhomme
Jun 22, 2016·Clinical EEG and Neuroscience·Martha Itzhel G RamírezDaniel San-Juan
Feb 18, 2018·Canadian Journal of Anaesthesia = Journal Canadien D'anesthésie·Michael S Avidan, Thomas J Graetz
Feb 11, 2020·Journal of Clinical Monitoring and Computing·Robert ZannerMatthias Kreuzer
Jul 12, 2017·Frontiers in Computational Neuroscience·Matthias Kreuzer
Aug 26, 2017·Der Anaesthesist·P MichelsM Söhle
Oct 8, 2020·European Journal of Anaesthesiology·Marie-Therese GeorgiiMatthias Kreuzer
May 12, 2021·Journal of Clinical Anesthesia·David P ObertMatthias Kreuzer

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