PMID: 9432316Mar 1, 1997Paper

Time of Helicobacter pylori eradication assessment following treatment

Helicobacter
G A NeilM L Skoglund

Abstract

The most appropriate time to assess accurately Helicobacter pylori eradication following treatment has been debated, with recommendations ranging from 1 to 3 months. The purpose of this study was to validate the assessment of H. pylori eradication 1 month following treatment. Three randomized, double-blind, active-controlled clinical trials were conducted in patients with endoscopically verified, active duodenal ulcers and H. pylori infection. Patients were treated with various treatment regimens of omeprazole plus amoxicillin. Ulcer healing, H. pylori eradication, and ulcer relapse were examined. Patients underwent repeat endoscopy and biopsy at 1 and 6 months following treatment (or sooner if symptoms returned) to determine the recurrence of ulcers and H. pylori status. To determine the accuracy of measuring H. pylori eradication at 1 month posttreatment, we compared the H. pylori status at 1 month and 6 months following treatment. In a combination of treatment groups and studies, a total of 384 evaluable patients represented data at both time points and were included in the analysis. Of those eradicated at 1 month posttreatment, 94% (141 of 150) remained eradicated at 6 months posttreatment. The proportion of patients with H...Continue Reading

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Citations

Jan 6, 2001·Digestive and Liver Disease : Official Journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver·V De FrancescoD Faleo
Dec 17, 2003·Journal of Gastroenterology and Hepatology·Chieko KatoKazuyuki Suzuki
Aug 26, 1998·Journal of Gastroenterology and Hepatology·A G FraserL Moore
Feb 14, 2007·Journal of Gastroenterology and Hepatology·Yao-Jong YangJiunn-Jong Wu
Mar 12, 2008·World Journal of Gastroenterology : WJG·Yaron Niv
Oct 17, 2007·Digestive Diseases and Sciences·Yaron NivKarin Achiel
Apr 30, 2017·World Journal of Gastrointestinal Oncology·Juan E CorralDouglas R Morgan
Aug 2, 2017·Journal of Gastroenterology and Hepatology·Varocha MahachaiDavid Graham
May 16, 2000·The American Journal of Gastroenterology·W D CheyU Murthy
Sep 1, 2005·The American Journal of Gastroenterology·Javier P Gisbert
Jan 12, 2010·FEMS Microbiology Reviews·James D Oliver
Sep 20, 2019·Journal of Cellular and Molecular Medicine·Yan Sun, Jun Zhang
Dec 29, 1998·Scandinavian Journal of Gastroenterology·J P GisbertA García-Plaza
Nov 2, 2016·Gut·P MalfertheinerUNKNOWN European Helicobacter and Microbiota Study Group and Consensus panel
Jun 10, 2000·Alimentary Pharmacology & Therapeutics·A ZulloA F Attili
Jul 27, 2001·Alimentary Pharmacology & Therapeutics·A ZulloS Morini

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