Time to clearance of human papillomavirus infection by type and human immunodeficiency virus serostatus

International Journal of Cancer. Journal International Du Cancer
Jill KoshiolJennifer S Smith

Abstract

Persistent infection with high-risk human papillomavirus (HPV) is central to cervical carcinogenesis. Certain high-risk types, such as HPV16, may be more persistent than other HPV types, and type-specific HPV persistence may differ by HIV serostatus. This study evaluated the association between HPV type and clearance of HPV infections in 522 HIV-seropositive and 279 HIV-seronegative participants in the HIV Epidemiology Research Study (HERS, United States, 1993-2000). Type-specific HPV infections were detected using MY09/MY11/HMB01-based PCR and 26 HPV type-specific probes. The estimated duration of type-specific infections was measured from the first HPV-positive visit to the first of two consecutive negative visits. Hazard ratios (HRs) and 95% confidence intervals (CIs) for HPV clearance were calculated using Cox models adjusted for study site and risk behavior (sexual or injection drugs). A total of 1,800 HPV infections were detected in 801 women with 4.4 years median follow-up. HRs for clearance of HPV16 and related types versus low-risk HPV types were 0.79 (95% CI: 0.64-0.97) in HIV-positive women and 0.86 (95% CI: 0.59-1.27) in HIV-negative women. HRs for HPV18 versus low-risk types were 0.80 (95% CI: 0.56-1.16) and 0.57 (...Continue Reading

References

Jan 1, 1989·American Journal of Epidemiology·R M Mickey, S Greenland
Sep 20, 1995·Journal of the National Cancer Institute·G Y HoS Romney
Feb 1, 1994·The Journal of Infectious Diseases·A HildesheimM E Sherman
Nov 14, 1997·The New England Journal of Medicine·X W SunT C Wright
Feb 12, 1998·The New England Journal of Medicine·G Y HoR D Burk
Nov 26, 1999·The New England Journal of Medicine·K L WallinJ Dillner
Jan 5, 2000·Journal of Clinical Microbiology·P E GravittR J Apple
Aug 21, 2001·Journal of Acquired Immune Deficiency Syndromes : JAIDS·L S MassadS Melnick
Jan 5, 2002·JAMA : the Journal of the American Medical Association·N F SchlechtE L Franco
Mar 29, 2002·Journal of Clinical Pathology·F X BoschK V Shah
Aug 27, 2002·The Journal of Infectious Diseases·Anna R GiulianoKenneth Hatch
Feb 7, 2003·The New England Journal of Medicine·Nubia MuñozUNKNOWN International Agency for Research on Cancer Multicenter Cervical Cancer Study Group
Jun 26, 2003·The Journal of Infectious Diseases·Paula SchumanUNKNOWN HIV Epidemiology Research Study (HERS) Group
Jul 17, 2003·Journal of the National Cancer Institute·Howard D StricklerRobert D Burk
Jan 20, 2005·Journal of the National Cancer Institute·Mark SchiffmanUNKNOWN ALTS Group

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Citations

Oct 20, 2006·Der Hautarzt; Zeitschrift für Dermatologie, Venerologie, und verwandte Gebiete·R WieneckeA Kreuter
Sep 23, 2006·Nature Reviews. Cancer·Richard Roden, T-C Wu
Feb 5, 2009·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Yurii B ShvetsovMarc T Goodman
May 17, 2008·American Journal of Epidemiology·Jill KoshiolJennifer S Smith
Sep 1, 2007·Current Opinion in Oncology·Erna Milunka Kojic, Susan Cu-Uvin
Sep 1, 2007·Current Opinion in Oncology·Hugo De Vuyst, Silvia Franceschi
Aug 30, 2012·Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [et Al.]·Bishr AldabaghSarah T Arron
Oct 29, 2010·Journal of Translational Medicine·Luciano Mariani, Aldo Venuti
Jul 14, 2007·Infectious Agents and Cancer·Ralph P InsingaEliav Barr
Jun 28, 2011·Infectious Agents and Cancer·Michael OdidaElisabete Weiderpass
Jun 8, 2014·BMC Infectious Diseases·Igor A Korostil, David G Regan
Dec 21, 2010·Annual Review of Immunology·Ian H FrazerStephen R Mattarollo
Nov 28, 2014·Proceedings. Biological Sciences·Carmen Lía MurallTroy Day
Oct 21, 2011·Journal of Women's Health·Christine L CurryElizabeth A Stier
Dec 5, 2012·Vaccine·John DoorbarMargaret A Stanley
Feb 13, 2007·Current Opinion in Immunology·Graham R Leggatt, Ian H Frazer
May 4, 2011·Statistics in Medicine·C E MitchellJ S Smith
Jan 5, 2011·Immunological Reviews·Purnima BhatGraham R Leggatt
Jan 13, 2011·American Journal of Reproductive Immunology : AJRI·Brenna L Anderson, Susan Cu-Uvin
Apr 17, 2013·International Journal of Cancer. Journal International Du Cancer·Lauren E WilsonNicolas Wentzensen
Mar 11, 2015·Reviews in Medical Virology·John DoorbarIsao Murakami
Jul 5, 2013·International Journal of Cancer. Journal International Du Cancer·Jill KoshiolLigia A Pinto
Nov 16, 2010·The Lancet Infectious Diseases·Nienke J VeldhuijzenJanneke Hhm van de Wijgert
Oct 15, 2014·BioMed Research International·Juliana Reis MachadoRosana Rosa Miranda Corrêa
Mar 8, 2008·International Journal of Infectious Diseases : IJID : Official Publication of the International Society for Infectious Diseases·Ian Frazer
Oct 3, 2009·The Lancet Oncology·Cornelia L Trimble, Ian H Frazer
Jan 10, 2009·Journal of Acquired Immune Deficiency Syndromes : JAIDS·Sebastian VidelaUNKNOWN HIV-HPV Study Group

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