Time to face the challenge of multimorbidity. A European perspective from the joint action on chronic diseases and promoting healthy ageing across the life cycle (JA-CHRODIS)

European Journal of Internal Medicine
Graziano OnderJoint Action on Chronic Diseases and Promoting Healthy Ageing across the Life Cycle (JA-CHRODIS)

Abstract

Research on multimorbidity has rapidly increased in the last decade, but evidence on the effectiveness of interventions to improve outcomes in patients with multimorbidity is limited. The European Commission is co-funding a large collaborative project named Joint Action on Chronic Diseases and Promoting Healthy Ageing across the Life Cycle (JA-CHRODIS) in the context of the 2nd EU Health Programme 2008-2013. The present manuscript summarizes first results of the JA-CHRODIS, focuses on the identification of a population with multimorbidity who has a high or very high care demand. Identification of characteristics of multimorbid patients associated with a high rate of resource consumption and negative health outcomes is necessary to define a target population who can benefit from interventions. Indeed, multimorbidity alone cannot explain the complexity of care needs and further, stratification of the general population based on care needs is necessary for allocating resources and developing personalized, cost-efficient, and patient-centered care plans. Based on analyses of large databases from European countries a profile of the most care-demanding patients with multimorbidity is defined. Several factors associated with adverse h...Continue Reading

Associated Clinical Trials

References

Jun 24, 2000·JAMA : the Journal of the American Medical Association·D J BraunerG A Sachs
May 19, 2007·BMJ : British Medical Journal·Martin FortinMarjan van den Akker
May 31, 2008·American Journal of Public Health·Alessandra MarengoniLaura Fratiglioni
Mar 16, 2011·Ageing Research Reviews·Alessandra MarengoniLaura Fratiglioni
Apr 19, 2011·Current Drug Metabolism·Graziano OnderFrancesco Landi
Nov 15, 2011·European Journal of Internal Medicine·Alessandro NobiliPier Mannuccio Mannucci
Jul 17, 2012·JAMA : the Journal of the American Medical Association·Mary E TinettiCynthia M Boyd
Jul 24, 2014·European Journal of Internal Medicine·S CorraoUNKNOWN REPOSI Investigators

❮ Previous
Next ❯

Citations

Jun 2, 2016·Anesthesiology and Pain Medicine·Seyed Sajad RazaviMohammadreza Hajiesmaeili
Apr 26, 2016·BioMed Research International·A MarengoniG Onder
Jun 1, 2016·Global Heart·Jaana LindströmMarkku Peltonen
Mar 8, 2018·Journal of the American Geriatrics Society·Simon N EtkindFliss E M Murtagh
May 5, 2018·The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences·Davide L VetranoUNKNOWN Joint Action ADVANTAGE WP4 group
Sep 29, 2017·The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences·Davide L VetranoLaura Fratiglioni
Apr 11, 2018·International Journal of Integrated Care·Simone R de BruinUNKNOWN SUSTAIN consortium
Mar 29, 2018·International Journal of Integrated Care·Liesbeth Borgermans, Dirk Devroey
Sep 25, 2019·Primary Health Care Research & Development·Mieke J L BogerdMarcel E Reinders
Aug 1, 2019·Panminerva Medica·Maria B ZazzaraGraziano Onder
Dec 15, 2019·International Journal of Environmental Research and Public Health·Katie PalmerGraziano Onder
Dec 20, 2019·Aging Clinical and Experimental Research·Gianlorenzo ScaccabarozziRoberto Bernabei
Jul 2, 2020·International Journal of Integrated Care·Simone R de BruinUNKNOWN SUSTAIN consortium
Dec 23, 2016·The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences·Amaia Calderón-LarrañagaLaura Fratiglioni
Jan 4, 2018·PloS One·Ferrán Catalá-LópezRafael Aleixandre-Benavent
Nov 28, 2018·Therapeutic Advances in Drug Safety·Gregory M OuelletMary E Tinetti
May 16, 2019·The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences·Laura M PérezAmaia Calderón-Larrañaga
Dec 22, 2019·International Journal of Environmental Research and Public Health·Maria João ForjazOn Behalf Of The Chrodis Expert Group On Multimorbidity
Jan 25, 2017·Evidence-based Complementary and Alternative Medicine : ECAM·Kathryn CurtisJoel Katz
Dec 24, 2018·International Journal for Quality in Health Care : Journal of the International Society for Quality in Health Care·Gaby Anne WildenbosLinda Peute
Jun 14, 2019·Irish Journal of Medical Science·Stephanie DowlingWalter Cullen
Apr 28, 2020·BioMed Research International·Maria Gabriella MelchiorreUNKNOWN on behalf of ICARE4EU Consortium
Jun 21, 2020·Mechanisms of Ageing and Development·Graziano OnderAlessandra Marengoni
Mar 7, 2021·Journal of Clinical Medicine·Ljiljana Trtica MajnarićAndreas Holzinger
Oct 3, 2018·The Journal of Allergy and Clinical Immunology·Jean BousquetUNKNOWN Mobile Airways Sentinel Network (MASK) Study Group
May 1, 2021·Journal of Personalized Medicine·Alfredo CesarioGiovanni Scambia
Aug 8, 2021·Health Services Research·Lipika SamalDavid A Dorr

❮ Previous
Next ❯

Related Concepts

Related Feeds

Age-related Dementia

Dementias are a group of conditions, including Alzheimer's disease, vascular dementia, and frontotemporal dementia, characterized by deficiencies in cognitive abilities. Age-related dementia refers to dementias that occur in older individuals, usually 60+ years old, in contrast to early-onset dementia. Follow the latest research on age-related dementia here.

Aging-Associated Metabolic Disorders

Age is associated with many metabolic disorders including cardiovascular diseases, type 2 diabetes, stroke and heart disease. The mediators in aging process have been suggested to play a part in the cellular processes responsible for these metabolic disorders. Here is the latest research on aging-associated metabolic disorders.