Abstract
The purpose of this study was to examine the change in incidence pattern of oesophageal cancer in the Côte-d'Or region (Burgundy, France). Data from the population-based cancer registry were used to study time trends between 1976 and 1993, according to sex, place of residence, subsite and histology. There was a non-significant increase in incidence of oesophageal cancer, by an average of +1.0% [confidence interval:-0.7; +2.8] per year in men and +2.0% [CI: -3.0; +6.9] in women. In men, variations in incidence were minor according to subsite and place of residence, among the six age groups studied. In contrast, there were important changes among histological types. Rates of squamous cell carcinoma remained stable, but those of adenocarcinoma increased significantly (P < 0.001). They represented 5.6% of known histological types, between 1976 and 1987, and 20.1% in 1991-3. Similar trends were observed in women. This rising incidence of adenocarcinomas, observed later than in the UK or the USA, started in 1987-90 and was particularly pronounced between 1991 and 1993. In view of this sharp increase in incidence of oesophageal adenocarcinomas, research on their aetiological determinants is urgently needed.
Citations
Aug 16, 2001·Cancer·E BollschweilerA H Hölscher
Jul 6, 2010·Gastric Cancer : Official Journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association·Shinichi Hasegawa, Takaki Yoshikawa
Feb 24, 2001·Current Problems in Cancer·R Wong, R Malthaner
Oct 17, 2001·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·D M ParkinS S Devesa
Jan 13, 2005·Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association·Angela Wong, Rebecca C Fitzgerald
Mar 16, 2002·Journal of Clinical Pathology·J P ByrneC B J Woodman
Jun 9, 2006·Diagnostic Pathology·Afshin Abdi-RadSara Emami
Oct 17, 2007·Digestive Diseases and Sciences·P A C GatenbyA Watson
Oct 7, 2009·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·Evangelos Chandanos, Jesper Lagergren
Nov 21, 2008·Diseases of the Esophagus : Official Journal of the International Society for Diseases of the Esophagus·Piers A C GatenbyAnthony Watson
Aug 3, 2000·International Journal of Epidemiology·A A BotterweckP A van Den Brandt
Jan 25, 2003·European Journal of Gastroenterology & Hepatology·Sarah C CobbeJohn F Dillon
Jan 16, 2008·BMC Cancer·Byoung Chul ChoNam Kyu Kim
Aug 22, 2000·Cancer·S ManfrediJ Faivre