Time trends of polybrominated diphenylether (PBDE) congeners in serum of Swedish mothers and comparisons to breast milk data

Environmental Research
Per Ola DarnerudAnders Glynn

Abstract

In the present study our main focus was blood serum levels and time trends of the fully brominated diphenyl ether (PBDE) BDE-209 in Swedish first-time mothers, as relatively a few human data on this congener are currently available. Also, levels and temporal trends in serum of other more commonly reported PBDE congeners and HBCD were studied. In an ongoing study on POPs in Uppsala Primiparas (POPUP), serum samples (N=413) from first-time mothers from 1996 to 2010 were used. Pooling of individual samples (5-25 individuals/pool, approx. 3 pools/year) resulted in 36 pooled samples used for PBDE/HBCD analysis on GC-LRMS. In addition, serum/breast milk correlations for PBDE and HBCD levels in 30 paired samples from individual mothers sampled 2010 were studied. The mean serum level of BDE-209 (1.3ng/g lipid wt.) was highest of all studied PBDE congeners, followed by BDE-47 and BDE-153. There was no significant temporal trend for BDE-209 during the study period, whereas the levels of BDE-47, BDE-99, BDE-100 and of HBCD decreased significantly in pooled serum 1996-2010. After omission of one outlier, a significant increasing trend was observed for BDE-153. The serum/milk PBDE quotients in paired individual samples from 2010 ranged from...Continue Reading

References

Dec 2, 1999·Journal of Toxicology and Environmental Health. Part a·D MeironytéA Bergman
Mar 17, 2001·Environmental Health Perspectives·P O DarnerudM Viluksela
May 10, 2002·Chemosphere·Cynthia A de Wit
Jul 5, 2003·Environmental Health Perspectives·Anita MazdaiRobert M Bigsby
Nov 24, 2004·Journal of Chromatography. a·José L Domingo
May 6, 2005·Environmental Science & Technology·Kaj ThuressonKristina Jakobsson
Oct 7, 2006·Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences·Cathrine ThomsenGeorg Becher
Jan 11, 2008·Molecular Nutrition & Food Research·Britta FängströmAke Bergman
Jun 17, 2008·International Journal of Hygiene and Environmental Health·Marie FrederiksenLisbeth E Knudsen
May 20, 2009·The AAPS Journal·Martin Bergstrand, Mats O Karlsson
Dec 19, 2009·Environmental Health Perspectives·Alicia J FraserMichael D McClean
Jun 5, 2010·Environmental Science & Technology·Paula I JohnsonJohn D Meeker
Jun 15, 2010·Environmental Science & Technology·Sonya LunderAke Bergman
Dec 21, 2010·Environmental Science & Technology·Larry L NeedhamPal Weihe
Feb 26, 2011·Environmental Science & Technology·David TrudelKonrad Hungerbühler
Jul 1, 2011·Environmental Health Perspectives·Deborah J WatkinsThomas F Webster
Dec 7, 2011·Ecotoxicology and Environmental Safety·Chunyan WangChangjiang Huang

❮ Previous
Next ❯

Citations

Sep 6, 2015·Current Environmental Health Reports·Susanna D MitroAmi R Zota
Sep 29, 2015·International Journal of Hygiene and Environmental Health·H FrommeW Völkel
Apr 14, 2016·International Journal of Hygiene and Environmental Health·Hermann FrommeWolfgang Völkel
Oct 23, 2015·Environmental Science and Pollution Research International·Jingzhi WangZhiqiang Yu
Oct 17, 2016·International Journal of Hygiene and Environmental Health·Lenka SochorováJana Pulkrabová
Apr 2, 2017·The Science of the Total Environment·Mandana BarghiYoon-Seok Chang
Sep 12, 2017·Environmental Toxicology and Chemistry·Katherine E RichmanCora J Young
Mar 15, 2018·Angewandte Chemie·Tunga SalthammerCharles J Weschler
Oct 19, 2016·Current Opinion in Oncology·Kate HoffmanHeather M Stapleton
Aug 31, 2017·Journal of Toxicology and Environmental Health. Part a·Hanne Friis BerntsenKarin Elisabeth Zimmer
Jan 15, 2020·Environmental Science and Pollution Research International·Darija KlinčićSnježana Herceg Romanić
Aug 15, 2018·International Journal of Environmental Research and Public Health·Immacolata Cristina NettorePaolo Emidio Macchia
Aug 24, 2017·Environmental Science and Pollution Research International·Jing Tang, Jin Xia Zhai
Dec 9, 2020·Xenobiotica; the Fate of Foreign Compounds in Biological Systems·Heldur HakkAnuradha Singh
Dec 24, 2018·The Science of the Total Environment·Joon-Woo KimTomohiko Isobe
Mar 19, 2021·EFSA Journal·UNKNOWN EFSA Panel on Contaminants in the Food Chain (CONTAM)Christiane Vleminckx
Dec 1, 2019·Environment International·Alba Iglesias-GonzálezBrice M R Appenzeller
Jul 20, 2018·ACS Omega·Erin MarkhamRainer Lohmann
May 4, 2020·Ecotoxicology and Environmental Safety·Yuting JinShangqin Chen

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.