Timelines in the insect brain: fates of identified neural stem cells generating the central complex in the grasshopper Schistocerca gregaria

Development Genes and Evolution
George Boyan, Yu Liu

Abstract

This study employs labels for cell proliferation and cell death, as well as classical histology to examine the fates of all eight neural stem cells (neuroblasts) whose progeny generate the central complex of the grasshopper brain during embryogenesis. These neuroblasts delaminate from the neuroectoderm between 25 and 30 % of embryogenesis and form a linear array running from ventral (neuroblasts Z, Y, X, and W) to dorsal (neuroblasts 1-2, 1-3, 1-4, and 1-5) along the medial border of each protocerebral hemisphere. Their stereotypic location within the array, characteristic size, and nuclear morphologies, identify these neuroblasts up to about 70 % of embryogenesis after which cell shrinkage and shape changes render progressively more cells histologically unrecognizable. Molecular labels show all neuroblasts in the array are proliferative up to 70 % of embryogenesis, but subsequently first the more ventral cells (72-75 %), and then the dorsal ones (77-80 %), cease proliferation. By contrast, neuroblasts elsewhere in the brain and optic lobe remain proliferative. Apoptosis markers label the more ventral neuroblasts first (70-72 %), then the dorsal cells (77 %), and the absence of any labeling thereafter confirms that central comp...Continue Reading

References

Nov 1, 1992·The Journal of Cell Biology·Y GavrieliS A Ben-Sasson
May 1, 1985·Proceedings of the National Academy of Sciences of the United States of America·J E Celis, A Celis
Dec 17, 1985·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·C Q DoeC S Goodman
Mar 1, 1980·Proceedings of the National Academy of Sciences of the United States of America·C S GoodmanN C Spitzer
Jun 1, 1983·The Journal of Comparative Neurology·J W Truman
Mar 1, 1980·The Journal of Cell Biology·R Bravo, J E Celis
Jun 15, 1993·The Journal of Comparative Neurology·G BoyanT Meier
Apr 29, 1994·Science·K WhiteH Steller
Feb 1, 1996·Current Opinion in Neurobiology·C Q Doe, J B Skeath
Jul 1, 1996·The Journal of Comparative Neurology·A Younossi-HartensteinV Hartenstein
Jul 22, 1996·The Journal of Comparative Neurology·M CayreA Strambi
Feb 15, 1997·Developmental Biology·A Younossi-HartensteinV Hartenstein
Jun 1, 1997·Trends in Neurosciences·H Reichert, G Boyan
Nov 27, 1998·The Journal of Comparative Neurology·V HartensteinA Lekven
Nov 15, 2000·The Journal of Cell Biology·I SumaraJ M Peters
Dec 20, 2002·Current Opinion in Neurobiology·Roland Strauss
Oct 10, 2003·Nature·Bret J Pearson, Chris Q Doe
Dec 3, 2003·Journal of Comparative Physiology. A, Neuroethology, Sensory, Neural, and Behavioral Physiology·M Mappes, U Homberg
May 26, 2004·The Journal of Experimental Biology·E ZudaireL M Montuenga
Jan 1, 2005·Trends in Neurosciences·Cédric Maurange, Alex P Gould
May 10, 2006·Molecular and Cellular Neurosciences·Maura StriginiDomna Karagogeos
May 19, 2006·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Wayne Pereanu, Volker Hartenstein

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Citations

Apr 9, 2016·Development Genes and Evolution·Nikolaus Dieter Bernhard KoniszewskiGregor Bucher
Sep 16, 2016·Frontiers in Behavioral Neuroscience·George S Boyan, Yu Liu
Mar 8, 2018·Development Genes and Evolution·George BoyanErica Ehrhardt
Jul 5, 2017·The Journal of Comparative Neurology·Jennifer K LovickVolker Hartenstein
Feb 6, 2020·Developmental Biology·Volker HartensteinJennifer K Lovick

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Apoptosis

Apoptosis is a specific process that leads to programmed cell death through the activation of an evolutionary conserved intracellular pathway leading to pathognomic cellular changes distinct from cellular necrosis