Timing-dependent effects of transcranial direct current stimulation with mirror therapy on daily function and motor control in chronic stroke: a randomized controlled pilot study

Journal of Neuroengineering and Rehabilitation
Wan-Wen LiaoChia-Ling Chen

Abstract

The timing of transcranial direct current stimulation (tDCS) with neurorehabilitation interventions may affect its modulatory effects. Motor function has been reported to be modulated by the timing of tDCS; however, whether the timing of tDCS would also affect restoration of daily function and upper extremity motor control with neurorehabilitation in stroke patients remains largely unexplored. Mirror therapy (MT) is a potentially effective neurorehabilitation approach for improving paretic arm function in stroke patients. This study aimed to determine whether the timing of tDCS with MT would influence treatment effects on daily function, motor function and motor control in individuals with chronic stroke. This study was a double-blinded randomized controlled trial. Twenty-eight individuals with chronic stroke received one of the following three interventions: (1) sequentially combined tDCS with MT (SEQ), (2) concurrently combined tDCS with MT (CON), and (3) sham tDCS with MT (SHAM). Participants received interventions for 90 min/day, 5 days/week for 4 weeks. Daily function was assessed using the Nottingham Extended Activities of Daily Living Scale. Upper extremity motor function was assessed using the Fugl-Meyer Assessment Scal...Continue Reading

References

Jul 1, 1988·The American Journal of Occupational Therapy : Official Publication of the American Occupational Therapy Association·L T CarterS V Lynch
Jun 22, 1999·Lancet·E L AltschulerV S Ramachandran
Jun 1, 1988·Journal of Motor Behavior·V B Brooks, S L Watts
May 6, 2005·Brain : a Journal of Neurology·Angelo QuartaroneHartwig R Siebner
Dec 13, 2005·Stroke; a Journal of Cerebral Circulation·Stella Maris MichaelsenMindy F Levin
Nov 1, 2007·The European Journal of Neuroscience·Andrea AntalWalter Paulus
Feb 21, 2009·Journal of Advanced Nursing·Marijke RensinkThóra Hafsteinsdóttir
Mar 19, 2009·Journal of Neuroengineering and Rehabilitation·Nadia BologniniFelipe Fregni
Apr 15, 2009·Cerebrovascular Diseases·Francisco Javier Carod-Artal, José Antonio Egido
Oct 17, 2009·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·Simone RossiUNKNOWN Safety of TMS Consensus Group
Dec 18, 2010·Stroke; a Journal of Cerebral Circulation·Katherine J SullivanPamela W Duncan
Feb 24, 2011·The Neuroscientist : a Review Journal Bringing Neurobiology, Neurology and Psychiatry·Charlotte J Stagg, Michael A Nitsche
Oct 8, 2011·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·A Bastani, S Jaberzadeh
Dec 27, 2011·Manual Therapy·Siobhan M Schabrun, Lucinda S Chipchase
Sep 12, 2012·Journal of Hand Therapy : Official Journal of the American Society of Hand Therapists·Andrew J ButlerKaren Guilkey
Feb 20, 2013·Archives of Physical Medicine and Rehabilitation·Ching-Yi WuHsiu-Wen Yang
Mar 27, 2013·Archives of Physical Medicine and Rehabilitation·Michelle L WoodburyPamela W Duncan
Aug 6, 2013·Neurorehabilitation and Neural Repair·Liesjet van DokkumIsabelle Laffont
Jan 31, 2014·Frontiers in Systems Neuroscience·Jared C HorvathJason D Forte
Mar 19, 2014·Brain Stimulation·Sarah WiethoffJohn C Rothwell
Aug 28, 2014·Neurorehabilitation and Neural Repair·Frederik J A DeconinckGeert J P Savelsbergh
Nov 22, 2014·Journal of Neurologic Physical Therapy : JNPT·Mary Ellen Stoykov, Sangeetha Madhavan
Dec 4, 2014·Brain Stimulation·Marta BortolettoCarlo Miniussi
Mar 31, 2015·Archives of Physical Medicine and Rehabilitation·Stephen J PageBrittani Blazak
Apr 2, 2015·The Neurohospitalist·Edward S ClaflinSandeep P Khot
May 23, 2015·Journal of Physical Therapy Science·Hyuk-Shin Cho, Hyun-Gyu Cha
May 23, 2015·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·L Tedesco TriccasG Verheyden
Sep 1, 2015·Journal of Neurology, Neurosurgery, and Psychiatry·Nyeonju KangJames H Cauraugh
Aug 1, 2016·Archives of Clinical Neuropsychology : the Official Journal of the National Academy of Neuropsychologists·Michelle E Mlinac, Michelle C Feng
Nov 9, 2016·Neuroscience·Stéphanie LefebvreYves Vandermeeren
Feb 22, 2017·Neuromodulation : Journal of the International Neuromodulation Society·Cristina RussoFelipe Fregni
Apr 16, 2017·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·Melanie K FlemingDi J Newham

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Jun 23, 2021·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·Sybren Van HoornwederRaf Meesen

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