Timing induction of labour at 41 or 42 weeks? A closer look at time frames of comparison: A review

Midwifery
Judit K J KeulenEsteriek de Miranda

Abstract

Postterm pregnancy is associated with increased perinatal risk. The WHO defines postterm pregnancy as a pregnancy at or beyond 42 weeks + 0 days, though currently labour is induced at 41 weeks in many settings. Guidelines on timing of labour induction are frequently based on the Cochrane systematic review 'Induction of labour for improving birth outcomes for women at or beyond term' in which is concluded that a policy of induction of labour is associated with fewer adverse perinatal outcome and fewer Caesarean sections. However, the included trials differed regarding the timing of induction, ranging from 39 to beyond 42 weeks while the upper limit of expectant management exceeded a gestational age of 42 weeks in most studies. to evaluate perinatal mortality, meconium aspiration syndrome and Caesarean section rate of trials comparing a policy of elective induction of labour and expectant management according to timeframes of comparison with a focus on studies within the 41-42 weeks' timeframe. Review. The systematic review of Cochrane was used as a starting point for assessing relevant trials and a search was performed for additional recent trials. We evaluated incidence and causes of perinatal mortality, incidence of meconium a...Continue Reading

Citations

Jan 30, 2020·PloS One·Dominiek CoatesCaroline Homer
Jul 16, 2020·The Cochrane Database of Systematic Reviews·Philippa MiddletonJudith C Gomersall
Jan 28, 2021·Journal of Clinical Ultrasound : JCU·Paolo RosatiAlessandra Familiari
May 24, 2020·Women and Birth : Journal of the Australian College of Midwives·J K J KeulenE de Miranda
Aug 1, 2021·Best Practice & Research. Clinical Obstetrics & Gynaecology·James Owen Drife

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