Timing of prostaglandin F(2alpha) release episodes and oxytocin receptor development during luteolysis in the cow

Animal Reproduction Science
G E Mann, G E Lamming

Abstract

The timing of PGF(2alpha) release and the timing and extent of the rise in endometrial oxytocin receptors was determined in relation to the timing of the progesterone fall during luteolysis in cycling cows. In cows undergoing luteolysis (n = 6), measurement of PGF(2alpha) metabolite in hourly plasma samples collected during daily 10 h sampling periods identified a total of 2.2+/-0.5 PGF(2alpha) release episodes per animal, each of 4.0+/-0.4 h duration. In cows in which luteolysis was not observed (n = 4) no PGF(2alpha) release episodes were identified. In a further three cows in which additional repeated uterine biopsies were collected on days 15, 17, 19, 21 and 23, endometrial oxytocin receptors were initially undetectable (<15 fmol/mg protein) but had increased to 120+/-19 fmol/mg protein prior to the initiation of PGF(2alpha) release episodes. Receptor concentrations then continued to increase reaching peak concentrations of 651+/-142 after luteolysis had been completed.

References

May 1, 1975·Journal of Reproduction and Fertility·W HaresignG E Lamming
Jan 1, 1991·Journal of Reproduction and Fertility·L J JennerG E Lamming
Aug 1, 1985·The Journal of Endocrinology·E L Sheldrick, A P Flint
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Citations

Jan 13, 2015·Animal Reproduction Science·Eduardo TrevisolJoão Carlos Pinheiro Ferreira
Oct 27, 2017·Allergy & Rhinology·Reza VaezeafsharJayakar V Nayak
Feb 8, 2008·Experimental Animals·Soraya Rasi GhaemiMojtaba Rezazadeh Valojerdi
Apr 22, 2015·Reproduction, Fertility, and Development·Mariko KuseKiyoshi Okuda
Dec 1, 2011·Reproduction, Fertility, and Development·Esben OstrupOlga Ostrup
Jul 23, 2021·Scientific Reports·Ramanathan Kasimanickam, Vanmathy Kasimanickam
Aug 30, 2021·Domestic Animal Endocrinology·M L OliveiraC M B Membrive

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