PMID: 317629Jan 1, 1979

Timolol and acetazolamide in the treatment of increased intraocular pressure (author's transl)

Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie. Albrecht Von Graefe's Archive for Clinical and Experimental Ophthalmology
A Scharrer, M Ober

Abstract

Twenty-four patients with open-angle glaucoma were tested to see if, and to what extent, timolol and acetazolamide produced a supplementary reduction of intraocular pressure. Twelve patients were treated with timolol eye drops, 0.5% b.d over a period of one week and then received one dose i.v. acetazolamide 250 mg which produced a statistically significant drop in intraocular pressure. Twelve patients with open-angle glaucoma who had been treated with acetazolamide 500 mg t.d.s. orally over a period of one week, received one drop of timolol 0.25% which produced a statistically significant additional effect. These results are discussed on the basis of the mode of action of the applied medications.

References

Oct 1, 1978·Acta Ophthalmologica·E Kerty, I Hørven
Apr 1, 1977·Archives of Ophthalmology·T J Zimmerman, H E Kaufman
Apr 1, 1977·Archives of Ophthalmology·T J Zimmerman, H E Kaufman
Jun 1, 1978·Archives of Ophthalmology·R L RadiusM E Langham

Citations

Jan 1, 1981·The British Journal of Ophthalmology·A Ohrström, O Kättström
Jan 1, 1992·Eye·F GunningF Grehn

Related Concepts

Acetazolamide Sodium, (Sterile)
Glaucoma
Physiologic Intraocular Pressure
Propanolamines
Timoptol

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Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie. Albrecht Von Graefe's Archive for Clinical and Experimental Ophthalmology
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