Tinidazole and metronidazole in the treatment of amoebic liver abscess

The Journal of International Medical Research
S N MathurV Rai


Tinidazole, a new drug effective against E histolytica, was studied in patients with amoebic liver abscess proved by aspiration of pus. A preliminary open evaluation in fourteen patients provided a cure in all cases. A subsequent comparative study against metronidazole in another twenty-two patients led to a cure in all eleven patients treated with tinidazole and in ten out of eleven patients treated with metronidazole. The response was faster in patients treated with tinidazole. Tinidazole was totally free from side-effects. Tinidazole is a noteworthy addition to anti-amoebic therapy.


Jun 28, 1973·The New England Journal of Medicine·F M Griffin
Aug 16, 1973·The New England Journal of Medicine·H Wilde


Jun 28, 2018·Indian Journal of Gastroenterology : Official Journal of the Indian Society of Gastroenterology·Sudhakar PandeySandeep Nijhawan

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