Tissue calcium content in piglets with inguinal or scrotal hernias or cryptorchidism

Journal of Comparative Pathology
C BeuermannC Knorr

Abstract

Scrotal and inguinal hernias are of great economic importance to the pig industry. These lesions are thought to result from incomplete closure of the inguinal ring and/or a patent processus vaginalis. Impairment of programmed cell death (PCD) may be involved in these abnormalities. As tissue Ca(2+) overload may be used as a measure of cell death, the aim of this study was to determine the tissue Ca(2+) content in samples of hernia sac, peritoneum, cremaster muscle and aqueous fluid from newborn piglets with scrotal or inguinal hernias (n=18) or cryptorchidism (n=18). Control samples from healthy piglets (n=20) were also evaluated. Tissue Ca(2+) content was determined by atomic absorption spectrophotometry. Significantly less Ca(2+) was found in the sacs (0.005 mg/g wt), peritoneal tissue (0.100 mg/g wt) and cremaster muscles (0.008 mg/g wt) of piglets with inguinal or scrotal hernias compared with control tissues (0.184, 0.144 and 0.048 mg/g wt for sacs, peritoneal tissue and cremaster muscles, respectively). These findings suggest that there may be perturbation of the apoptotic pathway in the urogenital tissues of affected piglets.

References

Feb 14, 1998·Anatomia, histologia, embryologia·S WenischG Hummel
Apr 15, 2000·Cells, Tissues, Organs·J M HutsonS Hasthorpe
Aug 16, 2000·Cell Calcium·L MissiaenH De Smedt
Jul 12, 2001·The Journal of Biological Chemistry·G Q WangH Rabinowich
Aug 21, 2002·Urologia Internationalis·F Cahit TanyelNebil Büyükpamukçu
Apr 5, 2003·Science·Nicolas Demaurex, Clark Distelhorst
Nov 25, 2003·Oncogene·Rosario RizzutoTullio Pozzan
Dec 23, 2004·Proceedings of the National Academy of Sciences of the United States of America·Scott A OakesStanley J Korsmeyer
Mar 8, 2005·Journal of Pediatric Surgery·John M Hutson, Suzanne Hasthorpe
Apr 4, 2008·Animal Genetics·C BeuermannC Knorr

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Citations

Jan 31, 2021·Genes·Ariene Fernanda Grando RodriguesMônica Corrêa Ledur

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