Tissue concentration, mRNA expression and stimulation of IGF-I in luteal tissue during the oestrous cycle and pregnancy of cows

Journal of Reproduction and Fertility
R EinspanierG Brem


The expression of IGF-I in bovine luteal tissue was demonstrated by parallel measurement of IGF-I tissue concentration and its mRNA; highest synthesis was observed during Days 12-17 of the cycle and the first months of pregnancy. Tissue levels of IGF-I increased from Days 1-5 to Days 12-17 of the cycle followed by a rapid decrease at luteolysis; there was a continuous decline from early pregnancy until Months 6-9. Microdialysis perfusion experiments with corpora lutea in vitro at Days 8-11 of the cycle revealed a major effect: release of progesterone and oxytocin were highly stimulated in a dose-dependent manner. We suggest that IGF-I could be important in regulating the function of the bovine corpus luteum and may act in an autocrine/paracrine way.


May 1, 1996·Theriogenology·W Hansel, G Cain
May 1, 1992·Molecular and Cellular Endocrinology·L S JonesJ L Pate
Jul 1, 1995·Domestic Animal Endocrinology·L J Spicer, S E Echternkamp
Jul 27, 2002·Domestic Animal Endocrinology·R WebbD G Armstrong
Nov 14, 2003·Reproductive Biology and Endocrinology : RB&E·Kiyoshi Okuda, Ryosuke Sakumoto
Apr 30, 2014·Animal : an International Journal of Animal Bioscience·J DupontM Reverchon
Jul 1, 1993·Fish Physiology and Biochemistry·F Le GacC Weil
Jul 1, 2004·Reproduction in Domestic Animals = Zuchthygiene·D Schams, B Berisha
Mar 8, 2008·Reproduction in Domestic Animals = Zuchthygiene·P LangendijkB Kemp
Nov 3, 2007·Reproduction in Domestic Animals = Zuchthygiene·M P GreenM G Hunter
Sep 19, 2002·The Journal of Veterinary Medical Science·Victor Chisha ZuluYutaka Sawamukai
Aug 16, 2008·Domestic Animal Endocrinology·M A VelazquezD C Wathes
Mar 1, 2002·Biology of Reproduction·Hiroaki TaniguchiKiyoshi Okuda
Jul 23, 1998·Biology of Reproduction·U SalliT D Braden
Apr 3, 2009·Current Protocols in Neuroscience·Vladimir I CheferToni S Shippenberg
Apr 23, 2008·Current Protocols in Neuroscience·T S Shippenberg, A C Thompson
Dec 13, 2006·Molecular Reproduction and Development·L T NicklinM G Hunter
Nov 13, 2009·Molecular Reproduction and Development·M SarkarBajram Berisha

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