Tissue distribution and temperature-dependence of Anguilla anguilla L. EROD activity following exposure to model inducers and relationship with plasma cortisol, lactate and glucose levels

Environment International
M Pacheco, M A Santos

Abstract

Anguilla anguilla L. ethoxyresorufin-O-deethylase (EROD) elevation by 2.7 microM beta-naphthoflavone (BNF) 3 days water exposure, or 4 mg/kg ip exposure, was studied in four different organs--liver, kidney, gills, and intestine. The results demonstrated a significant increase in liver EROD activity for the two previous conditions, whereas kidney EROD activity only increased during the intraperitoneal exposure. A. anguilla was also exposed during 8, 16, and 24 h to water contaminated with 2.7 microM BNF or benzo[a]pyrene (BaP) at 20 degrees C and 25 degrees C. Both compounds significantly increased liver EROD activity from 8 up to 24 h. There was no significant difference in liver EROD activity elevation by both compounds, either at 20 degrees C or 25 degrees C. Liver EROD activity was demonstrated to be one of the first warning systems concerning the presence of polycyclic aromatic hydrocarbons (PAHs) in water. A. anguilla 3 h exposure to diesel oil water-soluble fraction (DWSF) significantly increased plasma cortisol and significantly decreased plasma lactate. A prolonged exposure beyond 3 h, i.e. 4 h, 2, 3, 4, and 6 days to the previous conditions demonstrated a significant liver EROD activity elevation from Day 2 up to 6, an...Continue Reading

References

Nov 1, 1976·Mutation Research·P Maier, W Schmid
Aug 1, 1990·Ecotoxicology and Environmental Safety·M A SantosA Hall
Jan 1, 1987·Comparative Biochemistry and Physiology. C, Comparative Pharmacology and Toxicology·R E Thomas, S D Rice
Mar 1, 1988·Toxicology and Industrial Health·C R ClarkM Katchen
Aug 1, 1987·Fundamental and Applied Toxicology : Official Journal of the Society of Toxicology·H P WitschiM R Guerin
Jan 1, 1981·Comparative Biochemistry and Physiology. C: Comparative Pharmacology·P Lindström-SeppäO Hänninen
Nov 1, 1984·Archives of Environmental Contamination and Toxicology·L Lowe-Jinde, A J Niimi
Jan 1, 1981·Environmental Mutagenesis·T R HendersonC R Clark
Sep 1, 1982·General and Comparative Endocrinology·G J Leach, M H Taylor
Jan 1, 1994·Environmental and Molecular Mutagenesis·R H McKeeR T Przygoda
Jan 1, 1993·Fundamental and Applied Toxicology : Official Journal of the Society of Toxicology·M L HaaschJ J Lech
Oct 1, 1996·Ecotoxicology and Environmental Safety·M A Santos, M Pacheco
Feb 11, 1999·Comparative Biochemistry and Physiology. Part C, Pharmacology, Toxicology & Endocrinology·D R Buhler, J L Wang-Buhler
Jul 1, 1957·American Journal of Clinical Pathology·S REITMAN, S FRANKEL

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Citations

Oct 7, 2009·Ecotoxicology·Caroline Geeraerts, Claude Belpaire
Jun 19, 2012·Fish Physiology and Biochemistry·Aliakbar Hedayati, Abdolreza Jahanbakhshi
May 26, 2004·Ecotoxicology and Environmental Safety·V L MariaM A Santos
Feb 29, 2008·Ecotoxicology and Environmental Safety·I AhmadM A Santos
Mar 21, 2007·Ecotoxicology and Environmental Safety·Juliana Delatim SimonatoCláudia B R Martinez
Dec 17, 2002·Ecotoxicology and Environmental Safety·V L MariaM A Santos

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