PMID: 7007740Jan 1, 1981Paper

Tissue isoantigens A, B, and H in carcinoma of the cervix uteri: their clinical significance

Journal of Surgical Oncology
S GuptaA Rani

Abstract

A specific red cell adhesion test was done in 243 patients with carcinoma of the cervix uteri and showed the presence of isoantigens in only 27.16% of the patients with infiltrating squamous cell carcinoma. There was a gradual loss of isoantigens during the development of carcinoma. The test can be usefully employed in studying the evolution of the disease. The negativity of the test was found to increase as clinical severity of the disease increases. Also, the highest percentage (57.57%) of retained isoantigen was found in large-cell nonkeratinizing carcinoma, a well-differentiated type for the cervix. Follow-up studies suggest that the loss of antigen indicates probably metastasis and a poor prognosis.

References

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Citations

Sep 13, 2008·Diagnostic Pathology·Ernesto Moro-Rodríguez, Emilio Alvarez-Fernández
Dec 19, 2015·Tumour Biology : the Journal of the International Society for Oncodevelopmental Biology and Medicine·Jitti HanprasertpongThiti Atjimakul
Mar 1, 1986·Journal of Surgical Oncology·S N DasS Gupta
Dec 30, 2016·Future Science OA·Seth K Rummel, Rachel E Ellsworth

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