Tissue post-classification using the measured acoustic signals during 355 nm laser atherectomy procedures.

Journal of Biophotonics
Ziv AlperovichAmiel A Ishaaya

Abstract

The current laser atherectomy technologies to treat patients with challenging (to-cross) total chronic occlusions with a step-by-step (SBS) approach (without leading guide wire), are lacking real-time signal monitoring of the ablated tissues, and carry the risk for vessel perforation. We present first time post-classification of ablated tissues using acoustic signals recorded by a microphone placed nearby during five atherectomy procedures using 355 nm solid-state Auryon laser device performed with an SBS approach, some with highly severe calcification. Using our machine-learning algorithm, the classification results of these ablation signals recordings from five patients showed 93.7% classification accuracy with arterial vs nonarterial wall material. While still very preliminary and requiring a larger study and thereafter as commercial device, the results of these first acoustic post-classification in SBS cases are very promising. This study implies, as a general statement, that online recording of the acoustic signals using a noncontact microphone, may potentially serve for an online classification of the ablated tissue in SBS cases. This technology could be used to confirm correct positioning in the vasculature, and by this,...Continue Reading

References

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Feb 1, 2006·Journal of Endovascular Therapy : an Official Journal of the International Society of Endovascular Specialists·John R LairdUNKNOWN LACI Investigators
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Jan 10, 2014·Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions·Krishna J Rocha-SinghMichael R Jaff
Nov 26, 2015·EuroIntervention : Journal of EuroPCR in Collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology·Roberto LorenzoniMarco Roffi
Jan 21, 2017·Journal of Biophotonics·Amir HerzogWacław Kuczmik
Dec 19, 2018·Cardiovascular Revascularization Medicine : Including Molecular Interventions·Nicolas W ShammasUNKNOWN EX-PAD-03 Investigators
Apr 16, 2019·Journal of Biophotonics·Ziv AlperovichAmiel A Ishaaya
Aug 14, 2019·Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions·John RundbackNicolas W Shammas

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Citations

Aug 19, 2021·Gefässchirurgie : Zeitschrift für vaskuläre und endovaskuläre Chirurgie : Organ der Deutschen und der Österreichischen Gesellschaft für Gefässchirurgie unter Mitarbeit der Schweizerischen Gesellschaft für Gefässchirurgie·Jörg Teßarek, Alexander Oberhuber

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