Tissue-resident T cells in hepatitis B: A new target for cure?

The Journal of Experimental Medicine
Fabian J Bolte, Barbara Rehermann

Abstract

A hallmark of chronic hepatitis B virus (HBV) infection is the functional impairment and depletion of antiviral T cells. In this issue of JEM, Pallett et al. (https://doi.org/10.1084/jem.20162115) identify a reservoir of functional HBV-specific T cells among liver-resident T cells.

References

Jul 26, 2005·Immunity·Masanori IsogawaFrancis V Chisari
Feb 27, 2010·Journal of Hepatology·Mala K Maini, Anna Schurich
Oct 29, 2013·Nature Immunology·Laura K MackayThomas Gebhardt
Jan 21, 2014·Immunity·Su-Hyung Park, Barbara Rehermann
Jan 28, 2015·The Journal of Immunology : Official Journal of the American Association of Immunologists·Laura K MackayThomas Gebhardt
Dec 22, 2015·Nature Reviews. Immunology·Scott N Mueller, Laura K Mackay
May 10, 2016·Nature Medicine·Andrew S IshizukaRobert A Seder
May 21, 2017·The Journal of Experimental Medicine·Laura J PallettMala K Maini

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Citations

Dec 18, 2018·Frontiers in Immunology·Karin SteinbachDoron Merkler
Aug 6, 2019·Frontiers in Immunology·Yanan Wang, Cai Zhang
Jan 6, 2021·International Journal of Molecular Sciences·Ji Won Han, Eui-Cheol Shin

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Methods Mentioned

BETA
biopsies

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