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Tissue-specific cancer paradox and mutation rates

bioRxiv

Dec 15, 2014

Valentina Agoni

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Abstract

Some genes have ubiquitous expression patterns in an individual's cells, thus a paradox exists whereby mutations in such genes are only strongly associated with cancers of specific tissues. As these genes are ubiquitously expressed in the body's cells and thereby have functions in -pote...read more

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Tissue Specificity
Cell Body of Neuron
Mutation Abnormality
Histocompatibility Testing
Disease Susceptibility
Genes
Total Tissue
Protein Expression
Malignant Neoplasms
1
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  • Tissue-specific cancer paradox and mutation rates

    bioRxiv

    Dec 15, 2014

    Valentina Agoni

    PMID: 990012658

    DOI: 10.1101/012658

    Abstract

    Some genes have ubiquitous expression patterns in an individual's cells, thus a paradox exists whereby mutations in such genes are only strongly associated with cancers of specific tissues. As these genes are ubiquitously expressed in the body's cells and thereby have functions in -pote...read more

    Mentioned in this Paper

    Tissue Specificity
    Cell Body of Neuron
    Mutation Abnormality
    Histocompatibility Testing
    Disease Susceptibility
    1
    Paper Details
    References
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