Tissue-specific expression of the 79B actin gene during Drosophila development

Developmental Biology
C L Courchesne-Smith, S L Tobin

Abstract

We report temporal and tissue-specific patterns of expression of the 79B actin gene in Drosophila. The pattern of accumulation of 79B actin transcripts was determined and compared to the expression of a 79B actin promoter fused to the Escherichia coli beta-galactosidase reporter gene. This chimeric gene contained approximately 4 kb of 5' flanking DNA from the 79B actin gene. We found that beta-galactosidase activity in transformants was localized in the same tissues and possessed the same developmental timing as the transcripts of the 79B actin gene. Expression is limited to tubular-type muscles found predominantly in the thorax and leg, including the direct flight muscles, pleurosternal muscles, and muscles of the various leg segments. In addition, the 79B actin gene is expressed in muscles which support the head and abdomen, in the scutellar pulsatile organ, and in abdominal muscles which are present only in male flies.

References

Dec 1, 1977·Proceedings of the National Academy of Sciences of the United States of America·F SangerA R Coulson
Jun 13, 1966·Biochemical and Biophysical Research Communications·D T Denhardt
Feb 1, 1980·Cell·E A FyrbergK L Kindle
Oct 25, 1980·Journal of Molecular Biology·F SangerB A Roe
Oct 22, 1982·Science·G M Rubin, A C Spradling
Sep 24, 1983·Nucleic Acids Research·G M Rubin, A C Spradling
Mar 1, 1984·Cell·P A Lawrence, P Johnston

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Citations

Jul 14, 1999·BioEssays : News and Reviews in Molecular, Cellular and Developmental Biology·S Roy, K VijayRaghavan
Jun 1, 1993·Comparative Biochemistry and Physiology. B, Comparative Biochemistry·N Mounier, J C Sparrow
Oct 1, 1994·Insect Biochemistry and Molecular Biology·M He, D S Haymer
Apr 29, 1997·Proceedings of the National Academy of Sciences of the United States of America·D A GaileyJ C Hall
Mar 25, 2016·Biochemistry and Molecular Biology Education : a Bimonthly Publication of the International Union of Biochemistry and Molecular Biology·Vanesa AdameRichard M Cripps
Jan 10, 2006·Vitamins and Hormones·Edward M Berger, Edward B Dubrovsky
Jan 11, 2018·Developmental Dynamics : an Official Publication of the American Association of Anatomists·Tracy E Dohn, Richard M Cripps
Jul 1, 2005·Physiological Reviews·Scott L Hooper, Jeffrey B Thuma
Mar 16, 2019·Development·Ashley A DeAgueroRichard M Cripps
Jul 29, 2021·Scientific Reports·Han-Qing LiangShuo-Yang Wen

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