PMID: 11335130May 4, 2001Paper

Tissue-specific expression of the transcriptionally regulated serum and glucocorticoid-inducible protein kinase (Sgk) during mouse embryogenesis

Mechanisms of Development
E LeeG L Firestone

Abstract

In situ hybridization of mouse embryo whole mounts and sagittal sections revealed a tissue- and stage-specific expression pattern of the transcriptionally regulated serum and glucocorticoid-inducible protein kinase (sgk) during embryogenesis. Sgk expression is first observed at embryonic day 8.5 (E8.5) in the decidua and yolk sac, and then during developmental stages E9.5 through E12.5 this kinase is highly localized in the heart chamber, otic vesicle, blood vessels surrounding the somites, and lung buds. At the later stages of mouse embryogenesis, E13.5 through E16.5, sgk expression becomes highly concentrated in brain (choroid plexus), distal epithelium and the terminal bronchi/bronchioles, adrenal gland, liver, thymus and intestines, remains high in heart tissue, and is expressed at a low level in the other embryonic tissues.

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Citations

Jul 9, 2009·Current Opinion in Nephrology and Hypertension·Florian LangVolker Vallon
Feb 8, 2006·Annual Review of Physiology·Johannes LoffingOlivier Staub
Jan 13, 2005·Reproductive Biology and Endocrinology : RB&E·Eduardo A CallegariGeula Gibori
Mar 14, 2002·Proceedings of the National Academy of Sciences of the United States of America·Kuen J TsaiEminy H Y Lee
Jun 23, 2010·Developmental Dynamics : an Official Publication of the American Association of Anatomists·Catarina CatelaNadia Rosenthal
Aug 16, 2016·International Journal of Molecular Sciences·Yiyun LouFan Jin
Nov 15, 2001·Science's STKE : Signal Transduction Knowledge Environment·F Lang, P Cohen
Mar 29, 2007·Reproduction, Fertility, and Development·Xiang-Shun Cui, Nam-Hyung Kim
Oct 25, 2006·Stress : the International Journal on the Biology of Stress·Neeltje G van GemertMarian Joëls
Nov 25, 2003·American Journal of Physiology. Gastrointestinal and Liver Physiology·Tatjana CoricCecilia M Canessa
Jun 23, 2004·American Journal of Physiology. Lung Cellular and Molecular Physiology·Christie P ThomasRussell F Husted
Jun 4, 2021·Genes to Cells : Devoted to Molecular & Cellular Mechanisms·Yukihiro HaradaOsamu Nakagawa

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