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Tissue-specific regulation of insulin receptor mRNA levels in rats with STZ-induced diabetes mellitus

Diabetes

Sep 1, 1992

Leonardo Alberto SechiM Schambelan

PMID: 1386819

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Abstract

In rats with STZ-induced diabetes mellitus, a reduction in insulin secretion is associated with increased insulin binding in the liver, muscle, fat, and kidney, but not in the brain. To test the hypothesis that tissue-specific modulation of insulin receptors (IRs) in STZ-induced diabete...read more

Mentioned in this Paper

Insulin Receptor beta Subunit
Nucleic Acid Hybridization Procedure
Weighing Patient
Streptozotocin Diabetes
Dose-Response Relationship, Drug
RNA, Ribosomal, 28S
Genomic Hybridization
Brain
Novolin
Metabolic Control
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  • Tissue-specific regulation of insulin receptor mRNA levels in rats with STZ-induced diabetes mellitus

    Diabetes

    Sep 1, 1992

    Leonardo Alberto SechiM Schambelan

    PMID: 1386819

    DOI:

    Abstract

    In rats with STZ-induced diabetes mellitus, a reduction in insulin secretion is associated with increased insulin binding in the liver, muscle, fat, and kidney, but not in the brain. To test the hypothesis that tissue-specific modulation of insulin receptors (IRs) in STZ-induced diabete...read more

    Mentioned in this Paper

    Insulin Receptor beta Subunit
    Nucleic Acid Hybridization Procedure
    Weighing Patient
    Streptozotocin Diabetes
    Dose-Response Relationship, Drug

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