Tissue-specific regulation of the concentration of calbindin D28K mRNA in the developing chicken.

Life Sciences
S FerrariE Drusiani

Abstract

A BamHI-HindIII restriction fragment containing the 5'-terminal portion of the gene encoding chicken Calbindin D28K was sequenced and used as a probe in Northern-blot hybridizations to RNA extracted from the brain and intestine of chickens at various stages of development. In both tissues Calbindin D28K mRNA consists of a family of three species, which differ by size. In the intestine Calbindin D28K mRNAs appear at hatching and reach a peak at day 7. In the brain the same RNA species are easily detected at least 7 days before hatching, show a moderate increase at hatching and remain essentially constant during the first 10 days of adult life. The concentration of Calbindin D28K mRNAs in the intestine is strictly dependent on Vitamin D, while it is not in the cerebellum.

References

Dec 1, 1977·Proceedings of the National Academy of Sciences of the United States of America·F SangerA R Coulson
Apr 20, 1988·Journal of Molecular Biology·P W WilsonD E Lawson
Oct 1, 1986·Proceedings of the National Academy of Sciences of the United States of America·W Hunziker
Mar 1, 1973·Archives of Biochemistry and Biophysics·A J HitchmanJ E Harrison
May 1, 1967·Proceedings of the Society for Experimental Biology and Medicine·F A KallfelzR H Wasserman
Jul 1, 1983·Proceedings of the National Academy of Sciences of the United States of America·W HunzikerA W Norman
Jul 1, 1983·Analytical Biochemistry·A P Feinberg, B Vogelstein
May 13, 1982·Brain Research·K G BaimbridgeC O Parkes
May 6, 1966·Science·R H Wasserman, A N Taylor

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Citations

Jun 27, 2002·Journal of the Association for Research in Otolaryngology : JARO·Hakim HielPaul A Fuchs
Jul 1, 1990·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·R W ChesneyK Jolly

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