Tissue transplantation as an analytic and therapeutic tool in hereditary anemias

Allogenic therapies are generated in large batches from unrelated donor tissues such as bone marrow. In contrast, autologous therapies are manufactures as a single lot from the patient being treated. Here is the latest research on allogenic and autologous therapies.

Tissue transplantation as an analytic and therapeutic tool in hereditary anemias

Abstract

References

Implantation of normal blood-forming tissue in radiated genetically anemic hosts

SPLEEN-COLONY FORMATION IN ANEMIC MICE OF GENOTYPE WW

Citations

Biochemical and functional characterization of proteoglycans produced by Sl/Sld murine bone marrow stromal cell lines

The role of stem cell factor in mobilization of peripheral blood progenitor cells: synergy with G-CSF

Megakaryocytes in steel mutant mice

Stem cell factor (SCF), a novel hematopoietic growth factor and ligand for c-kit tyrosine kinase receptor, maps on human chromosome 12 between 12q14.3 and 12qter

The regulation of hemopoiesis in the spleen

Animal models of inherited hematologic disease

Fetal erythropoiesis in steel mutant mice. I. A morphological study of erythroid cell development in fetal liver

Capacity of adult steel (SI/SId) and dominant spotting (W/Wv) mouse skin to support melanogenesis

Mast-cell precursors in the skin of mouse embryos and their deficiency in embryos of Sl/Sld genotype

The Steel factor

Role of accessory cells in B lymphocyte progenitor differentiation

Clonal nature of mast-cell clusters formed in W/Wv mice after bone marrow transplantation

Hematopoietic stem cells

Bone-marrow microenvironment defect in congenital hypoplastic anemia

Normal blood cells of anemic genotype in teratocarcinoma-derived mosaic mice

Cellular regulation in Friend virus induced erythroleukemia. Studies with anemic mice of genotype Sl/Sld

The effect of recombinant mast cell growth factor on purified murine hematopoietic stem cells

Measurement of KIT ligand/stem cell factor: clinical and biochemical significance

The relation between erythropoiesis and plasma erythropoietin levels in normal and genetically anaemic mice during prolonged hypoxia or after whole-body irradiation

The response of W-W v and Sl-Sl d anaemic mice to haemopoietic stimuli

Studies on the defective haematopoietic microenvironment of Sl/Sl d mice

Foetal erythropoiesis in steel mutant mice. II. Haemopoietic stem cells in foetal livers during development

Effects of recombinant human erythropoietin on anaemic W/Wv and Sl/Sld mice

Dissecting the hematopoietic microenvironment. I. Stem cell lodgment and commitment, and the proliferation and differentiation of erythropoietic descendants in the S1-S1d mouse

Expression of congenital defects in the haemopoietic micro-environment: pre-natal erythropoiesis in anaemic 'Steel' (Slj-Slj) mice

Development of haematopoietic colonies on the macrophage layer formed in the peritoneal cavity of S1/S1d mice

Differential effects of microenvironmentally presented interleukin 3 versus soluble growth factor on primitive human hematopoietic cells

The effects of hematopoietic growth factors on neurite outgrowth

History of bone marrow transplantation

Membrane antigen expression during hemopoietic differentiation.

Macrophage regulation of myelopoiesis is altered by exposure to the benzene metabolite hydroquinone

Recent progress in the discovery and invention of novel hematopoietic cytokines

Bone marrow connective tissue and the haemopoietic microenvironment

Differentiation and transdifferentiation of mast cells; a unique member of the hematopoietic cell family

Human long-term bone marrow cultures in aplastic anemia.

The role of stem cell factor in the hematopoietic system

Transplantation of male germ line stem cells restores fertility in infertile mice

Clinical significance of long-term cultures of myeloid blood cells

Role of marrow stromal cells in the establishment of a transformed lymphoblastic B-cell line from a normal human subject.

Friend leukaemia virus-transformed cells, unlike normal stem cells, form spleen colonies in Sl/sld mice

W/Wv marrow stromal cells engraft and enhance early erythropoietic progenitors in unconditioned Sl/Sld murine recipients

The c-kit-encoded tyrosine kinase regulates the proliferation of early pre-B cells

Differentiation of germ cells in seminiferous tubules transplanted to testes of germ cell-deficient mice of W/Wv and Sl/Sld genotypes

Hemopoietic colonies on the chorioallantoic membrane of the chick embryo: induction by embryonic, adherent, non-hemopoietic spleen cells

The effects of steel mutation on testicular germ cell differentiation

The competitive ability of stem cells from mice with Hertwig's anemia

Effect of the mi allele on mast cells, basophils, natural killer cells, and osteoclasts in C57Bl/6J mice.

Organ interactions in the regulation of hematopoiesis: in vitro interactions of bone, thymus, and spleen with bone marrow stem cells in normal, Sl/Sld and W/Wv mice

Collagen synthesis by murine bone marrow cell culture.

Hemopoiesis in spleen and bone marrow cultures

Related Concepts

Related Feeds

Allogenic & Autologous Therapies

Related Papers

The response of W-W v and Sl-Sl d anaemic mice to haemopoietic stimuli

Proof of whole-cell implant in therapy of W-series anemia

Studies on the defective haematopoietic microenvironment of Sl/Sl d mice

Analysis of erythroid homeostatic mechanisms in normal and genetically anaemic mice

Implantation of normal blood-forming tissue in radiated genetically anemic hosts