Tizanidine does not affect the linear relation of stretch duration to the long latency M2 response of m. flexor carpi radialis.

Experimental Brain Research
Carel G M MeskersJ H Arendzen

Abstract

The long latency M2 electromyographic response of a suddenly stretched active muscle is stretch duration dependent of which the nature is unclear. We investigated the influence of the group II afferent blocker tizanidine on M2 response characteristics of the m. flexor carpi radialis (FCR). M2 response magnitude and eliciting probability in a group of subjects receiving 4 mg of tizanidine orally were found to be significantly depressed by tizanidine while tizanidine did not affect the significant linear relation of the M2 response to stretch duration. The effect of tizanidine on the M2 response of FCR is supportive of a group II afferent contribution to a compound response of which the stretch duration dependency originates from a different mechanism, e.g., rebound Ia firing.

References

Jul 1, 1979·The Journal of Physiology·J G ColebatchE K Potter
Sep 1, 1976·Journal of Neurophysiology·P E CragoZ Hasan
Apr 1, 1992·The Journal of Physiology·E Palmer, P Ashby
Mar 1, 1991·Trends in Neurosciences·P B Matthews
May 1, 1985·Journal of Neurophysiology·B Calancie, P Bawa
Jul 1, 1981·Journal of Neurophysiology·J C HoukP E Crago
Jun 1, 1994·The European Journal of Neuroscience·E JankowskaL E Dyrehag
Nov 1, 1994·Journal of Neurology, Neurosurgery, and Psychiatry·M EmreR C Roberts
Apr 1, 1996·Anesthesia and Analgesia·T J MiettinenM Scheinin
Apr 1, 1996·Electroencephalography and Clinical Neurophysiology·S J FellowsJ Noth
Sep 1, 1996·Experimental Brain Research·J ErikssonE Jankowska
Oct 9, 1998·The Journal of Physiology·E JankowskaJ Czarkowska-Bauch
Jun 22, 2000·Statistics in Medicine·R C LittellR Natarajan
Jan 26, 2006·Journal of Neuroscience Methods·Alfred C SchoutenFrans C T van der Helm
Feb 18, 2006·The Journal of Physiology·George LourençoVéronique Marchand-Pauvert
Mar 22, 2008·Current Biology : CB·Isaac L KurtzerStephen H Scott
Dec 3, 2008·Experimental Brain Research·Jasper SchuurmansFrans C T van der Helm

❮ Previous
Next ❯

Citations

Sep 25, 2010·Journal of Computational Neuroscience·Jasper SchuurmansAlfred C Schouten
Mar 1, 2012·Experimental Brain Research·J Andrew Pruszynski, Stephen H Scott
Dec 27, 2011·Journal of Electromyography and Kinesiology : Official Journal of the International Society of Electrophysiological Kinesiology·Jan S GroenewegenCarel G M Meskers
Oct 7, 2015·Frontiers in Integrative Neuroscience·Carel G M MeskersAlfred C Schouten
Feb 18, 2015·Frontiers in Integrative Neuroscience·Isaac L Kurtzer
Sep 4, 2018·The Journal of Physiology·Brian C HorslenMark G Carpenter
Jan 31, 2014·Journal of Neurophysiology·Isaac KurtzerStephen H Scott
Jan 5, 2018·Experimental Brain Research·Isaac KurtzerS H Scott

❮ Previous
Next ❯

Software Mentioned

SPSS

Related Concepts

Related Feeds

Barrel cortex

Here is the latest research on barrel cortex, a region of somatosensory and motor corticies in the brain, which are used by animals that rely on whiskers for world exploration.