TNF and ROS Crosstalk in Inflammation

Trends in Cell Biology
Heiko BlaserDirk Brenner

Abstract

Tumor necrosis factor (TNF) is tremendously important for mammalian immunity and cellular homeostasis. The role of TNF as a master regulator in balancing cell survival, apoptosis and necroptosis has been extensively studied in various cell types and tissues. Although these findings have revealed much about the direct impact of TNF on the regulation of NF-κB and JNK, there is now rising interest in understanding the emerging function of TNF as a regulator of the generation of reactive oxygen species (ROS) and reactive nitrogen species (RNS). In this review we summarize work aimed at defining the role of TNF in the control of ROS/RNS signaling that influences innate immune cells under both physiological and inflammatory conditions.

References

Jan 5, 2002·Physiological Reviews·Wulf Dröge
May 3, 2002·Blood·Frank M Torti, Suzy V Torti
Jun 1, 2002·Science·Guoqing Chen, David V Goeddel
Mar 2, 2006·Molecular and Cellular Biology·Takehiko UeyamaThomas L Leto
Jun 17, 2006·The Journal of Clinical Investigation·Pham My-Chan DangJamel El-Benna
Jul 18, 2006·Biochemical and Biophysical Research Communications·Young Min ChungYoung Do Yoo
Jul 29, 2006·FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology·Han-Ming Shen, Shazib Pervaiz
Sep 15, 2006·Cytokine·Sophie RoussetAnne-Marie Cassard-Doulcier
Oct 5, 2007·The Journal of Biological Chemistry·Nicole DeferCatherine Pavoine
Apr 22, 2008·Clinical and Experimental Immunology·L I FilippinR M Xavier
Apr 29, 2008·Free Radical Biology & Medicine·Douglas D ThomasDavid A Wink
May 30, 2008·Seminars in Immunopathology·J David LambethRobert A Clark
Nov 7, 2008·Genes and Immunity·M J H Coenen, P K Gregersen
Apr 10, 2009·Trends in Immunology·Malin HultqvistRikard Holmdahl
Apr 14, 2009·Antioxidants & Redox Signaling·Derick HanNeil Kaplowitz
May 15, 2009·Antioxidants & Redox Signaling·Thomas L LetoTakehiko Ueyama
Sep 22, 2009·PloS One·Colleen M SnyderNavdeep S Chandel
Oct 14, 2009·Current Opinion in Cell Biology·Dirk Brenner, Tak W Mak
Nov 7, 2009·Free Radical Biology & Medicine·Kyril TurpaevJean-Claude Drapier
Nov 12, 2009·Apoptosis : an International Journal on Programmed Cell Death·Seung Baek LeeYoung Do Yoo
Dec 17, 2009·Cell Death and Differentiation·T Vanden BergheP Vandenabeele
Jan 5, 2010·Current Opinion in Cell Biology·Dana E Christofferson, Junying Yuan
Jan 5, 2010·Free Radical Biology & Medicine·Magdalena L Circu, Tak Yee Aw
Jan 30, 2010·FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology·Yolande KroviarskiPham My-Chan Dang
Feb 6, 2010·Science·Frederic GeissmannKlaus Ley
Mar 23, 2010·Cell·Sergei I GrivennikovMichael Karin
Mar 23, 2010·Cell·Carl Nathan, Aihao Ding

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Citations

Mar 13, 2016·Archives of Biochemistry and Biophysics·Eleonora CremoniniPatricia I Oteiza
Nov 5, 2016·Biochimica Et Biophysica Acta·Maureen Redza-Dutordoir, Diana A Averill-Bates
Nov 24, 2016·Journal of Biochemical and Molecular Toxicology·Qian ZhangWensen Jin
Dec 17, 2016·Molecular Nutrition & Food Research·Nitin ShivappaInge Huybrechts
Sep 15, 2016·Scientific Reports·Sefayet KaracaBülent E Sekerel
Mar 7, 2017·American Journal of Obstetrics and Gynecology·Roberto RomeroAdi L Tarca
Dec 17, 2016·Brazilian Dental Journal·Taisa Nogueira PansaniCarlos Alberto de Souza Costa
Apr 20, 2017·International Journal of Molecular Sciences·Yusuke KandaFutoshi Okada
Apr 27, 2017·Foods·Eric Banan-Mwine DaliriByong H Lee
Jun 24, 2017·Pharmacology & Therapeutics·Rama MalaviyaDebra L Laskin
Jan 23, 2018·Naunyn-Schmiedeberg's Archives of Pharmacology·Orawan WongmekiatAnongporn Kobroob
Dec 1, 2017·Journal of Occupational Health·Tahmina AfrozMariko Murata
Dec 15, 2017·Nucleic Acids Research·Jia Jia ChanYvonne Tay
Dec 3, 2017·Clinical Oral Investigations·Aletéia M M FernandesGottfried Schmalz
Oct 13, 2017·Advanced Materials·Di-Wei ZhengXian-Zheng Zhang
Jan 8, 2017·American Journal of Physiology. Lung Cellular and Molecular Physiology·Xiaofei CongXiaoli Zhao
Dec 23, 2017·Evidence-based Complementary and Alternative Medicine : ECAM·Min Soo KimKyung Song
Apr 28, 2018·Cell Proliferation·Qiangsheng HuBo Zhang
Nov 2, 2017·The Journal of Experimental Medicine·Yu Matsuzawa-IshimotoKen Cadwell
Jun 30, 2016·Hypertension·Nathan P Rudemiller, Steven D Crowley
Aug 1, 2018·Stem Cells Translational Medicine·Juliana RedondoClaire M Rice
Sep 15, 2018·Acta Biochimica Et Biophysica Sinica·Huifang HouNing Huang
Feb 12, 2019·Free Radical Research·Hirofumi FujitaHideyo Ohuchi
Mar 29, 2019·JCI Insight·Maarten M SteinzJohanna T Lanner
May 14, 2019·Dalton Transactions : an International Journal of Inorganic Chemistry·Tong YuChunru Wang
Dec 22, 2017·Signal Transduction and Targeted Therapy·Jingwen JiangCanhua Huang
Aug 9, 2017·Cellular and Molecular Life Sciences : CMLS·Darío Acuña-CastroviejoGermaine Escames
Dec 20, 2017·Nature Immunology·Cathleen HolzeAndreas Pichlmair
Oct 22, 2019·BioFactors·Kiruthika SundarrajEkambaram Perumal

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