To delay or not to delay a frozen embryo transfer after a failed fresh embryo transfer attempt?

Fertility and Sterility
Samuel Santos-RibeiroChristophe Blockeel

Abstract

To evaluate if increasing the interval between a failed fresh embryo transfer and a subsequent frozen embryo transfer (FET) cycle has any effect on clinical pregnancy rates (CPRs). Retrospective cohort study. University-based tertiary referral center. Women who underwent at least one FET after ovarian stimulation for in vitro fertilization (IVF) and a failed fresh embryo transfer attempt from January 2010 to November 2014. We divided our sample according to the "timing" of the first FET (TF-FET), defined by the interval between oocyte retrieval and the FET cycle start date. The start of the FET was classified as either immediate (≤22 days after oocyte retrieval) or delayed (>22 days after oocyte retrieval). None. CPR after the first FET. A total of 1,183 FET cycles (performed in 1,087 women) were included in our study. No significant differences were found between the immediate and delayed FET groups regarding age, number of oocytes retrieved, number of good-quality embryos produced, embryo developmental stage at FET, and number of frozen embryos transferred. Most importantly, the CPRs of the first FET did not differ significantly according to the TF-FET (32.5% after immediate FET vs. 31.7% after delayed FET), even after adjust...Continue Reading

References

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Citations

Sep 15, 2017·The Australian & New Zealand Journal of Obstetrics & Gynaecology·Chloe HigginsBeverley Vollenhoven
Dec 6, 2019·Human Reproduction·Christophe BlockeelAnja Pinborg
Jan 4, 2018·Journal of Assisted Reproduction and Genetics·Leah KayeClaudio Benadiva
Jun 20, 2020·Journal of Assisted Reproduction and Genetics·Jialyu HuangYanping Kuang
Oct 31, 2020·International Journal of Gynaecology and Obstetrics : the Official Organ of the International Federation of Gynaecology and Obstetrics·Xiao TianZhen-Gao Sun
Feb 18, 2021·Human Reproduction Update·Sara J BergenheimAnja Pinborg
Apr 10, 2021·Gynecological Endocrinology : the Official Journal of the International Society of Gynecological Endocrinology·Monica PailisYoel Shufaro
Apr 15, 2021·Reproductive Medicine and Biology·Roberto MatorrasSonia Borjaba

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