To sleep or not to sleep: neuronal and ecological insights

Current Opinion in Neurobiology
Ada Eban-RothschildLuis de Lecea

Abstract

Daily, animals need to decide when to stop engaging in cognitive processes and behavioral responses to the environment, and go to sleep. The main processes regulating the daily organization of sleep and wakefulness are circadian rhythms and homeostatic sleep pressure. In addition, motivational processes such as food seeking and predator evasion can modulate sleep/wake behaviors. Here, we discuss the principal processes regulating the propensity to stay awake or go to sleep-focusing on neuronal and behavioral aspects. We first introduce the neuronal populations involved in sleep/wake regulation. Next, we describe the circadian and homeostatic drives for sleep. Then, we highlight studies demonstrating various effects of motivational processes on sleep/wake behaviors, and discuss possible neuronal mechanisms underlying their control.

Citations

Dec 6, 2017·Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology·Ada Eban-RothschildLuis de Lecea
Sep 19, 2018·The Journal of Clinical Investigation·Qian-Xing ZhuangJing-Ning Zhu
Jul 31, 2019·Journal of Neuroscience Research·Benjamin SmarrChristopher S Colwell
Aug 24, 2019·Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology·Anne RichardsThomas C Neylan
Aug 14, 2020·Physiological Reviews·Eus J W Van Someren
Apr 20, 2019·Frontiers in Neuroscience·Shinya FujiiMichael Lazarus
Dec 14, 2018·Postgraduate Medical Journal·Rachael M KellyAndrew N Coogan
Aug 23, 2017·Current Psychiatry Reports·Katherine E MillerPhilip R Gehrman
Jun 14, 2018·The Journal of Experimental Biology·Alex C Keene, Erik R Duboue
May 21, 2019·Frontiers in Neuroscience·Edward C HardingWilliam Wisden
Jul 26, 2019·Surgery Today·Go Ueno, Nobuhisa Ohno
Jan 30, 2021·Frontiers in Neuroscience·Basma RadwanDipesh Chaudhury
Feb 27, 2021·Frontiers in Behavioral Neuroscience·William J Giardino, Matthew B Pomrenze
May 30, 2020·Current Opinion in Physiology·Laura E McKillop, Vladyslav V Vyazovskiy
Jul 4, 2020·Current Opinion in Physiology·Edward C HardingWilliam Wisden
Aug 7, 2021·Scientific Reports·Akiko AndoKazutoshi Cho
Oct 10, 2021·Scientific Reports·Margaret DriscollDivya Sitaraman
Oct 29, 2021·Science·Nicholas P Franks, William Wisden
Oct 29, 2021·Biological Reviews of the Cambridge Philosophical Society·Nitya P MohantyMaria Thaker
Dec 16, 2021·The FEBS Journal·José Manuel DuhartKyunghee Koh

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