To switch or not to switch: Intentions to switch to injectable PrEP among gay and bisexual men with at least twelve months oral PrEP experience

PloS One
Kathrine MeyersSarit A Golub

Abstract

Phase III trials of long-acting injectable (LAI) PrEP, currently underway, have great potential for expanding the menu of HIV prevention options. Imagining a future in which multiple PrEP modalities are available to potential users of biomedical HIV prevention, we investigated which factors might help direct a patient-physician shared-decision making process to optimize the choice of biomedical HIV prevention method. Participants (n = 105; ages 19-63; 46.7% men of color) were former participants in a PrEP demonstration project and had taken daily oral PrEP for ≥ 12 months. Participants were given information about LAI PrEP and asked whether they would be interested in switching from oral to LAI PrEP. Participants were also asked about specific pros/cons of LAI PrEP, PrEP attitudes and experiences, and personality factors. Two-thirds (66.7%) of current oral PrEP users would switch to LAI PrEP. Intention to switch was associated with product-level and psychosocial factors. Attitudes towards logistical factors (i.e. getting to regular clinic visits for recurring shots) featured more prominently than factors related to the physical experience of PrEP modality (i.e., concerns about injection pain) as motivators for switching. In a m...Continue Reading

References

Nov 10, 2004·BMC Medical Research Methodology·Alicia O'Cathain, Kate J Thomas
Jan 28, 2006·International Family Planning Perspectives·Young Mi KimKathryn Church
Feb 8, 2006·Journal of Anxiety Disorders·Brett Deacon, Jonathan Abramowitz
Mar 24, 2007·European Journal of Clinical Pharmacology·Anita KozyrskyjAmber Racher
Apr 27, 2010·Journal of Pediatric Health Care : Official Publication of National Association of Pediatric Nurse Associates & Practitioners·Ray LazarusAvy Violari
Oct 22, 2013·The Lancet Infectious Diseases·Kenneth K MugwanyaUNKNOWN Partners PrEP Study Team
Nov 21, 2013·Journal of Travel Medicine·Lorraine M NobleRon H Behrens
Mar 13, 2014·The Lancet Infectious Diseases·Jared M Baeten, Renee Heffron
May 3, 2014·Journal of Acquired Immune Deficiency Syndromes : JAIDS·Deborah DonnellConnie Celum
Aug 16, 2014·Annals of Behavioral Medicine : a Publication of the Society of Behavioral Medicine·Kristi E Gamarel, Sarit A Golub
Apr 29, 2015·AIDS Education and Prevention : Official Publication of the International Society for AIDS Education·Rafael E Pérez-FigueroaPerry N Halkitis
Sep 4, 2015·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Jonathan E VolkC Bradley Hare
Nov 17, 2015·Current Opinion in HIV and AIDS·Robert M Grant, Kimberly A Koester
Jan 23, 2016·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·David V GliddenRobert M Grant
Jul 28, 2016·AIDS Education and Prevention : Official Publication of the International Society for AIDS Education·Kathryn MacapagalBrian Mustanski
Jun 14, 2017·AIDS·Caroline FosterUNKNOWN CHERUB Investigators
Jul 6, 2017·Revista de saúde pública·Ana Paula SilvaMariângela Carneiro

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Citations

May 28, 2019·British Dental Journal·Van B Haywood, Fadi Al Farawati
Nov 7, 2019·Current Opinion in HIV and AIDS·Delivette CastorShannon Allen
Jan 23, 2021·Journal of the International AIDS Society·Gordon ManserghPatrick Sullivan
Nov 6, 2020·Journal of Acquired Immune Deficiency Syndromes : JAIDS·Matthew E LevyIrene Kuo

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