PMID: 29470904Jul 1, 2016Paper

TO THE PROTOCOL OF ANTIBIOTIC PROPHYLAXIS IN CARDIAC SURGERY

Anesteziologiia i reanimatologiia
E S Duman'yanV A Porhanov

Abstract

Guidelines recommend that duration of antibiotic prophylaxis in cardiac surgery should be no more than 48 h, but at the same time it has been suggested that a 24h or even a single dose may be sufficient. To define whether 24-hour antibiotic prophylaxis on the incidence of infectious complications in cardiac surgery compared to the 72-hour period. Materials andmethods. All 125 patients were operatedfrom 01.01.2014 till 01.10.2014. All preoperative, intra and postoperative data were analyzed. Group 1 (n = 56) - these patients were administered cefazolinfor 24 h antibiotic prophylaxis (3 g/day); group 2 (n = 69) -patients with cefazolin for 72 h antibiotic prophylaxis (1 g every 8 h). Pre and intraoperative characteristics were the same in both groups. Duration of stay in intensive care unit (ICU), postoperative hospitalization, sternomediastinitis frequency were also similar in both groups. The frequency of nosocomial pneumonia and rate ofprescription of antibiotics after antibiotic prophylaxis was significantly higher in group 1. 24-hour antibiotic prophylaxis does not increase the frequency of the surgical field's infection, but the frequency of postoperative pneumonia and change of antibiotic prophylaxis on antibiotic therapy ...Continue Reading

Related Concepts

Related Feeds

Bacterial Pneumonia (ASM)

Bacterial pneumonia is a prevalent and costly infection that is a significant cause of morbidity and mortality in patients of all ages. Here is the latest research.

Bacterial Pneumonia

Bacterial pneumonia is a prevalent and costly infection that is a significant cause of morbidity and mortality in patients of all ages. Here is the latest research.