PMID: 2484488Nov 1, 1989Paper

Tobacco smoke and malignant tumors. Analysis by birth cohorts from 1875 to 1935

Annali di igiene : medicina preventiva e di comunità
F La RosaF Trotta

Abstract

Over the last decades, the relationship between tobacco smoking and cancer has been studied utilizing all the models available to research. The epidemiological researches, that are carried out on human populations, constitute the study model which can provide definitive evidence on the considered association. Among the several cancer sites, cancer of the lung, oral cavity and pharynx, esophagus, larynx, pancreas and urinary bladder are the sites more directly related with smoking habits. In this research the relationship between these cancer sites and tobacco smoking was studied examining both the international literature, and applying the cohort analysis to Italian mortality data from 1950 to 1983. The birth cohorts considered were those from 1875 to 1935 and data on cancer deaths are derived from official ISTAT publications. The analysis of cohort variation was carried out utilizing the indirect standardization method. The data on tobacco consumption, from 1900 to 1985, was obtained from official publication of the Administration of the State Monopolies or from unpublished material kindly provided by the same Administration. Regarding lung cancer, literature data emphasize the relationship between the disease frequency and ag...Continue Reading

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