Toe walking after three: how serious could it be?

BMJ Case Reports
Linda-Marie UstarisRatna Basak

Abstract

A 4-year-old girl with no significant medical or family history presented with toe walking, leg pain, unsteady gait and frequent falls for 2 months. Examination revealed upper motor neuron signs in the lower extremities. Laboratory tests were normal including creatinephosphokinase and lactate dehydrogenase. Brain and lumbar spine MRI were normal. MRI cervical and thoracic spine showed a large intradural and extradural mass arising from the right C7 nerve root, widening of the neural canal with evidence of cord compression. She underwent C6-C7 laminectomy with excision of the tumour. Pathology revealed spindle cell tumour with extensive expression of S100 protein and CD56, with Ki-67 proliferation index of 1%-2% consistent with benign schwannoma. She made an excellent recovery following surgery and physiotherapy sessions. Review of literature shows rare reported case of schwannoma prior to the third decade of life.

References

Sep 1, 1990·Pediatrics in Review·M C Patterson, M R Gomez
Oct 25, 2001·Journal of Pediatric Orthopedics·J F PolicyJ Rose
Feb 6, 2007·Pediatric Neurology·Juan A Piantino, Alcy Torres
Sep 19, 2007·The Journal of Spinal Cord Medicine·Pamela E WilsonGerald H Clayton
Sep 29, 2009·Expert Reviews in Molecular Medicine·Dorianna Sandonà, Romeo Betto
Oct 5, 2010·Journal of Neurosurgery. Spine·Kamal R M WoodsDaniel J Won
Feb 3, 2011·Journal of Child Neurology·William J BarrowPasquale J Accardo
Mar 15, 2014·Journal of Applied Oral Science : Revista FOB·Suzely Adas Saliba MoimazNemre Adas Saliba
Feb 14, 2015·Journal of Neurology, Neurosurgery, and Psychiatry·Emily K MatheyCindy S-Y Lin
Jun 14, 2015·Current Problems in Surgery·Dawn M ColemanPeter K Henke
Dec 29, 2015·Current Opinion in Pediatrics·Joseph J RuzbarskyEmily Dodwell
Nov 28, 2016·Neuroimaging Clinics of North America·Mary Tenenbaum
Jul 19, 2017·Current Problems in Pediatric and Adolescent Health Care·Olga M MorozovaMackenzie E Brown

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