PMID: 6969767Aug 1, 1980Paper

Tolerance induction in mice selected for high or low antibody responsiveness

Journal of Immunogenetics
A M Heumann, C Stiffel

Abstract

Induction of tolerance to bovine serum albumin was studied in mice selected for high (H) or low (L) antibody responsiveness and in their F1 hybrids. No high or low zone tolerances were obtained in H mice whereas L mice were susceptible to tolerance induction by the two schedules. H mice were immunized by repeated injections of tolerogenic BSA for low zone tolerance induction but not after the administration of a single high dose of tolerogenic BSA. Resistance to tolerance induction is dominant in F1 hybrids.

References

Feb 1, 1975·Cellular Immunology·M L LukićS Leskowitz
Feb 1, 1979·Journal of Immunogenetics·A M Heumann, C Stiffel
Apr 1, 1974·Cellular Immunology·M Fujiwara, B Cinader
Nov 1, 1972·The Journal of Experimental Medicine·D M SilverH J Winn

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