PMID: 18707592Aug 19, 2008Paper

Tolerance to antimicrobial agents and persistence of Escherichia coli and cyanobacteria

Biochemistry. Biokhimii︠a︡
V D SamuilovA A Shestak

Abstract

Bacterial persistence is the tolerance of a small part of a cell population to bactericidal agents, which is attained by a suppression of important cell functions and subsequent deceleration or cessation of cell division. The growth rate is the decisive factor in the transition of the cells to the persister state. A comparative study of quickly growing Escherichia coli K-12 strain MC 4100 and cyanobacteria Synechocystis sp. PCC 6803 and Anabaena variabilis ATCC 29413 growing slowly was performed. The cyanobacterial cells, like E. coli cells, differed in sensitivity to antimicrobial substances depending on the growth phase. Carbenicillin inhibiting the synthesis of peptidoglycan, a component of the bacterial cell wall, and lincomycin inhibiting the protein synthesis gave rise to nucleoid decay in cells from exponential cultures of Synechocystis 6803 and did not influence the nucleoids in cells from stationary cultures. Carbenicillin suppressed the growth of exponential cultures and had no effect on cyanobacterial stationary cultures. A suppression of Synechocystis 6803 growth in the exponential phase by lincomycin was stronger than in the stationary phase. Similar data were obtained with cyanobacterial cells under the action of ...Continue Reading

References

May 21, 1999·Science·J W CostertonE P Greenberg
Jun 26, 2001·Biochemistry. Biokhimii︠a︡·V D SamuilovT A Fedorenko
Jan 22, 2004·FEMS Microbiology Letters·Iris KerenKim Lewis
Mar 24, 2004·Trends in Microbiology·Hanna Engelberg-KulkaRonen Hazan
Sep 21, 2004·Biochemistry. Biokhimii︠a︡·V D SamuilovD V Bezryadnov
Sep 24, 2004·Cytometry. Part a : the Journal of the International Society for Analytical Cytology·S M Stocks
Apr 6, 2005·Biochemistry. Biokhimii︠a︡·K Lewis
Sep 24, 2005·Journal of Cell Science·Hanna Engelberg-KulkaShahar Amitai
Aug 23, 2006·Antimicrobial Agents and Chemotherapy·Michael D LaFleurKim Lewis
Dec 5, 2006·Nature Reviews. Microbiology·Kim Lewis

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Citations

Jan 23, 2014·The Science of the Total Environment·Björn BerglundPer-Eric Lindgren
Apr 19, 2015·Journal of Microbiological Methods·Tylor J JohnsonWilliam R Gibbons
Mar 20, 2010·FEMS Microbiology Reviews·Juana María Navarro LlorensEsteban Martínez-García
Mar 24, 2017·FEMS Microbiology Reviews·Bram Van den BerghJan Michiels
May 30, 2019·International Journal of Molecular Sciences·Krystian Miazek, Beata Brozek-Pluska
Nov 1, 2021·Plant & Cell Physiology·Akiko Yoshihara, Koichi Kobayashi

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