Tomographic active optical trapping of arbitrarily shaped objects by exploiting 3D refractive index maps

Nature Communications
Kyoohyun Kim, YongKeun Park

Abstract

Optical trapping can manipulate the three-dimensional (3D) motion of spherical particles based on the simple prediction of optical forces and the responding motion of samples. However, controlling the 3D behaviour of non-spherical particles with arbitrary orientations is extremely challenging, due to experimental difficulties and extensive computations. Here, we achieve the real-time optical control of arbitrarily shaped particles by combining the wavefront shaping of a trapping beam and measurements of the 3D refractive index distribution of samples. Engineering the 3D light field distribution of a trapping beam based on the measured 3D refractive index map of samples generates a light mould, which can manipulate colloidal and biological samples with arbitrary orientations and/or shapes. The present method provides stable control of the orientation and assembly of arbitrarily shaped particles without knowing a priori information about the sample geometry. The proposed method can be directly applied in biophotonics and soft matter physics.

References

Aug 15, 2003·Nature·David G Grier
Nov 5, 2004·Optics Letters·Peter John RodrigoJesper Glückstad
Jan 9, 2007·Journal of the Optical Society of America. A, Optics, Image Science, and Vision·Stephen H Simpson, Simon Hanna
Oct 31, 2005·Optics Express·Ritesh AgarwalDavid Grier
Aug 26, 2009·Journal of Biophotonics·David J CarnegieKishan Dholakia
Dec 6, 2011·Optics Letters·Sanjit K Debnath, YongKeun Park
Feb 15, 2012·Optics Express·D PalimaJ Glückstad
Jun 21, 2012·Optics Express·Yongyin CaoHalina Rubinsztein-Dunlop
Feb 8, 2013·Optics Express·D B PhillipsS H Simpson
Jun 13, 2014·Optics Express·F SaglimbeniR Di Leonardo
Jan 13, 2015·The European Physical Journal. E, Soft Matter·B M MihiretieB Pouligny
Feb 15, 2015·Biomedical Microdevices·Álvaro BarrosoCornelia Denz
Feb 27, 2015·Scientific Reports·Glen R KirkhamKevin Shakesheff
Oct 28, 2015·Biomedical Optics Express·Jonghee YoonYongKeun Park

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Citations

Jan 26, 2018·Reports on Progress in Physics·Azra BahadoriPoul M Bendix
Feb 15, 2020·Journal of Physics. Condensed Matter : an Institute of Physics Journal·Rahul VaippullyBasudev Roy
Oct 11, 2019·Micromachines·Edison GerenaSinan Haliyo
May 16, 2018·Biomedical Optics Express·Ruilong LingLei Tian
Apr 3, 2021·Applied Optics·Vinoth BalasubramaniChau-Jern Cheng
May 18, 2021·Light, Science & Applications·Moosung LeeYongKeun Park
Jul 6, 2021·Biomedical Optics Express·Jiawei SunJürgen W Czarske
Jan 23, 2018·Langmuir : the ACS Journal of Surfaces and Colloids·Bradley RuppMichael A Bevan

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Methods Mentioned

BETA
optical diffraction tomography
optical diffraction
optical tweezers

Software Mentioned

MATLAB GUI
TOMOTRAP

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