Tongue thickness evaluation using ultrasonography can predict swallowing function in amyotrophic lateral sclerosis patients

Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology
Masahiro NakamoriMasayasu Matsumoto

Abstract

Dysphagia is a critical issue in amyotrophic lateral sclerosis (ALS) patients. An evaluation of swallowing function is important for assessing the risk of aspiration. We investigated the validity of tongue sonography compared with videofluoroscopic examination for ALS patients. We investigated 18 ALS patients. Nine subjects underwent repeated investigations. All of the subjects underwent tongue sonography and videofluoroscopic examination. Additionally, tongue sonography was evaluated in 18 age- and sex-matched healthy volunteers. To determine tongue thickness, we measured the vertical distance from the surface of the mylohyoid muscle to the tongue dorsum using ultrasonography. In the ALS patients, the tongue was significantly thinner than in healthy subjects. Tongue thickness was associated with body mass index and onset type in the ALS patients (p=0.006). Temporal analyses of videofluoroscopy revealed that tongue thickness was associated with oral preparatory and transit time (p=0.032) but not with pharyngeal transit time. Repeated measurement data revealed a decrease in tongue thickness over the course of the measurements (p=0.002). In ALS patients, reduced tongue thickness suggests disease progression and tongue dysfunction...Continue Reading

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Citations

Nov 2, 2016·PloS One·Masahiro NakamoriMasayasu Matsumoto
Oct 3, 2017·Continuum : Lifelong Learning in Neurology·Francis O Walker
Sep 30, 2020·PloS One·Masahiro NakamoriShinichi Wakabayashi
Jan 11, 2017·Neurotherapeutics : the Journal of the American Society for Experimental NeuroTherapeutics·Richard SmithGary Pattee
Jun 15, 2017·Amyotrophic Lateral Sclerosis & Frontotemporal Degeneration·Yu-Ichi NotoMatthew C Kiernan
Sep 27, 2020·Journal of Neurology·Masahiro NakamoriHirofumi Maruyama
Dec 5, 2018·Neuropathology : Official Journal of the Japanese Society of Neuropathology·Tomoyasu MatsubaraYuishin Izumi
Dec 29, 2020·Special Care in Dentistry : Official Publication of the American Association of Hospital Dentists, the Academy of Dentistry for the Handicapped, and the American Society for Geriatric Dentistry·Atsuko TamuraHaruka Tohara
Jun 5, 2021·PloS One·Masahiro NakamoriShinichi Wakabayashi
Aug 26, 2021·International Journal of General Medicine·Andrew HannafordNeil G Simon
Nov 9, 2021·Neurodegenerative Disease Management·Milena Magalhães AugustoLeandro Pernambuco

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