Too much of too little: xylitol, an unusual trigger of a chronic metabolic hyperchloremic acidosis.

European Journal of Pediatrics
David WilleVera Bernet

Abstract

Homeopathic globules are frequently used in children as a first-line treatment. Most of these globules are coated with sugar substitutes like xylitol; these substitutes are known for their laxative effect. Our patient shows that consumption of globules coated with xylitol does not have only laxative effects. It may cause indeed considerable weight loss and life-threatening enteral bicarbonate loss by diarrhea when overdosed in an infant.

References

Jun 1, 1989·The American Journal of Clinical Nutrition·E K SalminenP E Koivistoinen
Jan 1, 1981·Annual Review of Nutrition·Y M Wang, J van Eys
Nov 14, 2006·International Journal of Pediatric Otorhinolaryngology·Louis VernacchioAllen A Mitchell
May 9, 2007·Journal of Nutritional Science and Vitaminology·Tsuneyuki Oku, Sadako Nakamura
Mar 11, 2008·Pharmacoepidemiology and Drug Safety·Francesca Menniti-IppolitoRoberto Raschetti
May 3, 2008·The Journal of the American Dental Association·Kiet A LyMarilynn Rothen

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Citations

Nov 21, 2012·International Journal of Clinical Practice·P PosadzkiE Ernst
Oct 3, 2018·F1000Research·Siel DaelemansYvan Vandenplas

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