PMID: 9421222Jan 8, 1998Paper

Topical and systemic therapy for recurrent aphthous stomatitis

Seminars in Cutaneous Medicine and Surgery
L A MacPhail

Abstract

The cause of recurrent aphthous ulcers (RAU), the lesions of recurrent aphthous stomatitis, is incompletely understood but appears to involve immune system dysfunction. Treatment options include no treatment, treatment of associated systemic diseases or conditions (eg, celiac sprue, vitamin deficiencies), systemic medications, topical medications, conversion of the aphthous ulcer to a wound, and palliative treatments. The most effective treatments (systemic or topical corticosteroids, thalidomide) involve agents that suppress or modulate immune system function. In general, topical agents are preferred because they have fewer associated side effects; however, inability to obtain adequate contact time may limit their effectiveness. Adjunct pain control is sometimes necessary, either with pain medications or with adherent agents that coat the ulcers.

References

Jan 1, 1978·Journal of Oral Pathology·E A Graykowski, A Kingman
Jan 1, 1978·Journal of Oral Pathology·D WrayJ H Dagg
Jul 1, 1977·The British Journal of Oral Surgery·S J ChallacombeT Lehner
Jun 1, 1978·Oral Surgery, Oral Medicine, and Oral Pathology·D E FrostH Abrams
May 31, 1975·British Medical Journal·D WrayJ H Dagg
May 1, 1992·Journal of Oral Pathology & Medicine : Official Publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology·R Häyrinen-ImmonenY T Konttinen
Oct 1, 1992·Oral Surgery, Oral Medicine, and Oral Pathology·D GradyJ Greenspan
Oct 1, 1992·Journal of Oral Pathology & Medicine : Official Publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology·G Reyes-TeránS Ponce de León
Mar 1, 1992·Oral Surgery, Oral Medicine, and Oral Pathology·L A MacPhailJ S Greenspan
Jan 1, 1992·Journal of Oral Pathology & Medicine : Official Publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology·L J TaylorT J Peters
Jun 1, 1991·Oral Surgery, Oral Medicine, and Oral Pathology·L A MacPhailJ S Greenspan
Aug 1, 1991·Acta Odontologica Scandinavica·A PedersenL P Ryder
Feb 1, 1990·Oral Surgery, Oral Medicine, and Oral Pathology·R LandesbergR Insel
Nov 1, 1991·Journal of Oral Pathology & Medicine : Official Publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology·C O'FarrellyD G Weir
Sep 1, 1991·Journal of Oral Pathology & Medicine : Official Publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology·A NolanP J Lamey
Jan 1, 1991·Oral Surgery, Oral Medicine, and Oral Pathology·J A PhelanR S Klein
Mar 1, 1991·The Journal of Experimental Medicine·E P SampaioG Kaplan
Apr 1, 1991·The Medical Journal of Australia·R Bittoun
Jun 1, 1991·The Journal of the American Dental Association·M Colvard, P Kuo
Apr 1, 1990·Journal of Oral Pathology & Medicine : Official Publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology·L SalonenL Helldén
Jun 1, 1989·Journal of the American Academy of Dermatology·D GrinspanS Agüero
Jun 1, 1988·Oral Surgery, Oral Medicine, and Oral Pathology·B Rodu, C M Russell
Sep 1, 1988·Teratology·W Lenz
Jan 1, 1988·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·G P WormserM Reitano
Aug 1, 1985·Oral Surgery, Oral Medicine, and Oral Pathology·N W SavageB J Kruger
Jun 1, 1988·Archives of Otolaryngology--head & Neck Surgery·C B RuahW D Chasin
Sep 1, 1987·Oral Surgery, Oral Medicine, and Oral Pathology·L EisenbudB Kay
Dec 1, 1986·The Australasian Journal of Dermatology·R S Rogers, K P Hutton
Mar 1, 1972·Oral Surgery, Oral Medicine, and Oral Pathology·H R Stanley
Nov 1, 1970·Oral Surgery, Oral Medicine, and Oral Pathology·S ShapiroS J Chellemi
Dec 1, 1983·Oral Surgery, Oral Medicine, and Oral Pathology·H E SchroederK Sallay
Nov 1, 1982·Oral Surgery, Oral Medicine, and Oral Pathology·J A OlsonJ S Greenspan
Oct 1, 1995·The Journal of Pediatrics·M L de AsisJ Schliozberg
Feb 1, 1995·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·D L PatersonR J Kemp
Jul 1, 1994·Clinical Immunology and Immunopathology·A Pedersen, L P Ryder
Feb 1, 1994·Oral Surgery, Oral Medicine, and Oral Pathology·B C Muzyka, M Glick
Jan 1, 1994·The Journal of Dermatology·S M Lee, S H Lee
May 1, 1994·The Laryngoscope·M FriedmanL Taylor

❮ Previous
Next ❯

Citations

Feb 16, 2005·Alimentary Pharmacology & Therapeutics·S R Porter, J C Leao
Sep 26, 2003·American Journal of Clinical Dermatology·A Ross Kerr, Jonathan A Ship
Feb 9, 2010·Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG·Morteza PourahmadHamed Kashafi
Apr 12, 2003·Pharmacotherapy·Mark C Okafor
Dec 25, 2013·Clinical and Molecular Allergy : CMA·Adey HasanGuha Krishnaswamy
Dec 20, 2007·Oral and Maxillofacial Surgery Clinics of North America·Ellen Eisenberg
Jul 22, 2008·Clinics in Dermatology·Shereen Timani, Diya F Mutasim
Mar 15, 2003·The Journal of the American Dental Association·Crispian ScullyFrancina Lozada-Nur

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

American Journal of Health-system Pharmacy : AJHP : Official Journal of the American Society of Health-System Pharmacists
R W Barrons
Journal of Oral Pathology & Medicine : Official Publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology
Natalia LewkowiczH Tchórzewski
Acta otorrinolaringológica española
Diana Quijano, Mauricio Rodríguez
© 2021 Meta ULC. All rights reserved