Topical corticosteroid 'addiction'. A cause of perioral dermatitis

Postgraduate Medicine
K Wells, R T Brodell

Abstract

Acne rosacea, perioral dermatitis, and telangiectasia are all local side effects that can flare up when potent topical corticosteroids used on the face are withdrawn. The two cases of perioral dermatitis described here illustrate the nature of the addictive cycle caused by long-term use of these agents. To prevent side effects of topical corticosteroids used on the face, physicians need to avoid long-term prescriptions and shun superpotent agents entirely for this area. Pharmacists should not refill topical corticosteroid prescriptions without authorization. Patient education must emphasize the transient nature of flare-ups of itching and rash that occur when these agents are withdrawn. Systemic and topical antibiotics and corticosteroid-free antipruritics are the mainstays of therapy.

References

Sep 1, 1979·The British Journal of Dermatology·D S WilkinsonJ D Wilkinson
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Mar 1, 1979·Clinical and Experimental Dermatology·R E Cochran, J Thomson
May 1, 1976·Archives of Dermatology·J R MelletteD D Nuss
Mar 1, 1972·The British Journal of Dermatology·G Weber
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Mar 1, 1971·The British Journal of Dermatology·R Marks, M M Black
Jun 1, 1981·Journal of the American Academy of Dermatology·H J Cohen
Sep 1, 1982·Journal of the American Academy of Dermatology·H L ChanH I Maibach
Jun 1, 1964·Archives of Dermatology·R MIHAN, S AYRES

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Citations

Jun 6, 2002·Journal of the European Academy of Dermatology and Venereology : JEADV·S LjubojeviaeJ Lipozenèiae
Jun 6, 2002·Journal of the European Academy of Dermatology and Venereology : JEADV·T Jansen
Mar 14, 2014·American Journal of Clinical Dermatology·Therdpong Tempark, Tor A Shwayder
Jul 28, 2004·Postgraduate Medicine·Carrie A Oklota, Robert T Brodell

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