Topical cyclosporin A in the management of vernal keratoconjunctivitis

Eye
V Gupta, P K Sahu

Abstract

To study the efficacy of topical cyclosporin A in children with vernal keratoconjunctivitis in a prospective randomised double-masked trial. Twenty-four children between 5 and 16 years of age were randomly treated with cyclosporin A (CsA) and placebo (vehicle) and followed up for 4 months. Of the 12 patients given CsA, 11 showed symptomatic improvement by 7 days of starting treatment whereas only 3 patients in the placebo group showed mild symptomatic improvement. Topical cyclosporin is a safe and effective treatment in vernal keratoconjunctivitis.

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