PMID: 11913682Mar 27, 2002Paper

Topical estrogens combined with argon plasma coagulation in the management of epistaxis in hereditary hemorrhagic telangiectasia

The Annals of Otology, Rhinology, and Laryngology
W BerglerK Hörmann

Abstract

The aim of this study was to assess the value of topically applied estrogens in patients with hereditary hemorrhagic telangiectasia. Twenty-six patients with this disorder were treated with argon plasma coagulation and randomized into 2 groups: group A, which had postoperative application of estriol ointment (n = 14), and group B, which had postoperative application of dexpanthenol ointment (n = 12). Over a period of 12 months, the frequency and intensity of bleeding, the patient's satisfaction, and the success of the treatment were evaluated with a questionnaire. Before the operation, more than 90% of the patients in both groups complained of daily episodes of epistaxis. Twelve months after treatment, the frequency and intensity of bleeding had significantly decreased in group A as compared to group B. Of the patients in group A, 93% were satisfied with the treatment. Of the patients in group B, only 42% were satisfied with the treatment. In both groups, more than 90% of the patients were willing to undergo the same treatment again. The combined treatment approach with argon plasma coagulation and topical estriol enables us to significantly prolong the hemorrhage-free interval.

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Citations

May 17, 2006·Wiener klinische Wochenschrift·Haneen SadickKarl Hörmann
Mar 2, 2005·European Archives of Oto-rhino-laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery·Ilias KarapantzosVasilis Danielides
Feb 16, 2010·European Archives of Oto-rhino-laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery·Aysenur Meric TekerOrhan Gedikli
Jul 3, 2013·Expert Opinion on Biological Therapy·Theoni Kanellopoulou, Alexandra Alexopoulou
Jan 29, 2016·Thrombosis and Haemostasis·Roberto ZarrabeitiaLuisa M Botella
Jan 26, 2016·Acta Oto-laryngologica·Kazuhiko Minami, Tomoyuki Haji
Dec 31, 2015·Journal of Otolaryngology - Head & Neck Surgery = Le Journal D'oto-rhino-laryngologie Et De Chirurgie Cervico-faciale·Mark Bastianelli, Shaun J Kilty
Jan 18, 2015·European Archives of Oto-rhino-laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery·Jing ZhangChunsheng Wei
Jan 31, 2012·International Forum of Allergy & Rhinology·Holly BoyerGeorge Goding
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May 9, 2012·International Forum of Allergy & Rhinology·Nathan B Sautter, Timothy L Smith
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Sep 24, 2015·Angiogenesis·Helen ArthurWhitney Wooderchak-Donahue
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Jan 2, 2019·Laryngoscope Investigative Otolaryngology·Marci ClarkJeffrey B Hoag
Aug 24, 2019·Lasers in Surgery and Medicine·Arash AbiriEdward C Kuan

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