Topical Imiquimod Treatment of Lentigo Maligna.

Case Reports in Dermatology
F VenturaC Brito

Abstract

Lentigo maligna (LM) is the in situ phase of lentigo maligna melanoma, which may progress to invasive melanoma if left untreated. It mainly occurs on sun-exposed areas of elderly patients. The lesions can be large and conventional surgery can be difficult, particularly on the face. Recent reports indicate that topical imiquimod 5% cream is effective in the treatment of LM. It may be an alternative when surgery or other classical treatments are not possible in elderly patients. We describe an 80-year-old Caucasian woman with a 10-year history of a histologically verified extensive LM of the face. She was treated with imiquimod 5% cream once daily. After four months it showed complete clinical response. One year after the treatment the patient was still free from recurrence.

Citations

Feb 18, 2012·Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [et Al.]·Lixia Z EllisLeslie Stewart
Aug 3, 2011·Expert Review of Anticancer Therapy·Jeremy R EtzkornL Frank Glass
Aug 4, 2012·Actas dermo-sifiliográficas·E Samaniego, P Redondo
May 4, 2011·Actas dermo-sifiliográficas·E Nagore, R Botella-Estrada
Nov 29, 2014·Case Reports in Medicine·Sharad P Paul
Feb 1, 2019·Scientific Reports·Andrea Orlandi, Alice Mado Proverbio

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BETA
biopsy
biopsies

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