Topical insulin in neurotrophic keratopathy after resection of acoustic neuroma.

Archivos de la Sociedad Española de Oftalmología
V GalvisM A Gómez

Abstract

A patient with a history of surgical resection of an acoustic neuroma presented with involvement of both the left facial nerve and the left trigeminal nerve. She initially consulted for exposure keratitis, but two weeks later presented with an infectious keratitis. After taking the corneal sample, she presented with persistent epithelial defect, which did not respond to medical management. Topical insulin was indicated, and a decrease in the area of the lesion was seen in the following 5 days. A therapeutic contact lens was also placed at that time and finally, two weeks after the initiation of insulin, the epithelial defect completely closed. This was a complex case due to the confluence of facial paralysis, neurotrophic keratitis, and infectious keratitis, which finally had a successful outcome. Topical insulin can be an effective adjuvant therapy in cases of neurotrophic ulcers that do not respond to standard therapy.

References

Jan 1, 1994·Journal of Ocular Pharmacology·J D BartlettD J Pillion
Mar 24, 2004·Investigative Ophthalmology & Visual Science·Lynne J ShanleyMin Zhao
Aug 19, 2007·Archives of Ophthalmology·Ian S ZagonPatricia J McLaughlin
Jul 1, 1945·The British Journal of Ophthalmology·T R Aynsley
Apr 26, 2014·JAMA Ophthalmology·Kathryn J RayThomas M Lietman
Aug 3, 2014·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·Alexandre KarkasSébastien Schmerber
Jul 26, 2017·Cornea·Angeline L WangMichael C Struck
Dec 19, 2017·Operative Neurosurgery·William S GangeCharles S Bouchard

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Citations

Sep 22, 2020·European Journal of Ophthalmology·David Diaz-ValleJose M Benitez-Del-Castillo
Mar 30, 2021·Contact Lens & Anterior Eye : the Journal of the British Contact Lens Association·Deborah S JacobsFiona Stapleton
Feb 1, 2020·Archivos de la Sociedad Española de Oftalmología·S Martínez-Pizarro

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