Topical oxygen therapy stimulates healing in difficult, chronic wounds: a tertiary centre experience

Journal of Wound Care
Hanna KaufmanPaul Hayes

Abstract

Oxygen plays a central role in wound healing. Recent technological advances have miniaturised oxygen delivery systems, with novel topical oxygen therapy allowing patients to receive oxygen therapy 24 hours a day while remaining completely mobile. Here we aim to examine the efficacy and safety of continuous topical oxygen diffusion in a 'real-world' setting. Topical oxygen therapy (TOT) was evaluated in patients with chronic, non-healing wounds in a tertiary referral specialist clinic. The mean wound duration before TOT was 15 months. Regardless of treatment duration, in this previously non-healing group complete wound closure was observed in 32% of the total patients treated with the TOT device. However, optimal wound healing occurred when the device was used for >25 days, with an 83% wound area reduction and 47% wound closure rate seen in venous leg ulcers (VLUs) and a 74% reduction and a 57% wound closure rate in arterial foot ulcers. Use of TOT in chronic wounds stimulates a healing state. In our study, almost half of the previously non-healing wounds closed.

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Citations

Feb 15, 2020·The Journal of Dermatological Treatment·André OliveiraCatarina Pinto Reis
May 20, 2020·Journal of Wound Care·Hanna Kaufman
May 20, 2020·Journal of Wound Care·John Lantis
May 20, 2020·Journal of Wound Care·Ibby Younis
May 20, 2020·Journal of Wound Care·Johnson Boey
May 20, 2020·Journal of Wound Care·Johnson Boey
May 20, 2020·Journal of Wound Care·Harikrishna Kr Nair
May 20, 2020·Journal of Wound Care·Linda Hicks
May 20, 2020·Journal of Wound Care·Ibby Younis
Nov 27, 2020·Nanomaterials·Oana GherasimAlexandru Mihai Grumezescu
Jan 1, 2021·Drugs·Danielle Dixon, Michael Edmonds
Dec 4, 2020·World Journal of Clinical Cases·Shi-Yan RenRong-Ding Gao
Oct 14, 2021·Journal of Wound Care·Frances ConnaghanZena Moore

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