Topical treatment of pityriasis rubra pilaris with calcipotriol

The British Journal of Dermatology
P C van de Kerkhof, P M Steijlen

Abstract

From a clinical, histological and therapeutic point of view, psoriasis and pityriasis rubra pilaris share important characteristics. Recently, calcipotriol has been shown to be an effective treatment in psoriasis, and we report three patients with pityriasis rubra pilaris who showed a favourable response to topical therapy with calcipotriol. In one case, analysis of markers for epidermal growth, differentiation and inflammation revealed reduction of suprabasal expression of keratin 16, and the number of T lymphocytes, monocytes and macrophages. It is of interest that a reduction of the recruitment of cycling epidermal cells, which is a consistent response pattern during treatment of psoriasis, was not observed during treatment of pityriasis rubra pilaris.

References

Jan 1, 1989·The Journal of Investigative Dermatology·S de MareP C van de Kerkhof
Jan 1, 1987·Dermatologica·R HappleH Traupe
Dec 1, 1970·Archives of Dermatology·W R Knowles, M E Chernosky
Jun 1, 1966·Australian Journal of Dermatology·F E Anderson
Oct 1, 1984·The Journal of Clinical Investigation·W F RigbyM W Fanger
Mar 1, 1981·The British Journal of Dermatology·I G RalfsN A Wright
Nov 1, 1981·Archives of Dermatology·J Fleissner, R Happle
Mar 1, 1980·Clinical and Experimental Dermatology·W A Griffiths

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Citations

Sep 15, 2004·Der Hautarzt; Zeitschrift für Dermatologie, Venerologie, und verwandte Gebiete·S ArtikM Megahed
Jul 1, 1996·Clinics in Dermatology·K M Albers
Nov 19, 2002·Clinics in Dermatology·Jennifer L Parish
Mar 4, 2000·Clinics in Dermatology·E Nicolaidou, A D Katsambas
Jun 9, 2000·Clinical and Experimental Dermatology·C M NeessK Scharffetter-Kochanek
Mar 5, 1999·International Journal of Dermatology·M R Albert, B T Mackool
Mar 16, 2002·International Journal of Dermatology·Elisabeth A Holm, Gregor B E Jemec
Aug 1, 1997·The American Journal of the Medical Sciences·R A BonomoR A Salata
Feb 27, 2010·American Journal of Clinical Dermatology·Annette KleinSigrid Karrer
Sep 6, 2001·Clinics in Geriatric Medicine·A van VoorheesV P Werth
Aug 1, 1997·Journal of the American Academy of Dermatology·M H GrunwaldB Amichai
Jun 1, 1997·Journal of the American Academy of Dermatology·B D ClaytonW L White
Apr 25, 2006·Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics·Luis Edmundo Martinez CalixtoLida Radfar
Nov 10, 2006·The Journal of Dermatological Treatment·Daniel J PearceSteven R Feldman
Mar 19, 2014·Journal of Cutaneous Medicine and Surgery·Heidi Wat, Marlene Dytoc
Dec 17, 2017·Journal of the European Academy of Dermatology and Venereology : JEADV·S Roenneberg, T Biedermann
May 3, 2006·International Journal of Dermatology·Virendra N Sehgal, Govind Srivastava
Nov 7, 2019·Journal of Cutaneous Medicine and Surgery·Avee NaidooVincent Piguet
Jan 6, 2018·American Journal of Clinical Dermatology·Dingyuan WangHazel H Oon
Oct 1, 1996·The British Journal of Dermatology·S KienbaumT Ruzicka
Nov 1, 1995·Journal of the American Academy of Dermatology·J S Walsh, J A Fairley

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