Topical use of autologous platelet rich plasma in myringoplasty

Auris, Nasus, Larynx
Mohammad Waheed El-AnwarMohammad Abdel-Rhman Abdel-Salam Yacoup

Abstract

The aim of this study was to assess the topical use of autologous platelet rich plasma (PRP) to improve success rate of myringoplasty. This study was carried out on 64 patients with large dry central tympanic membrane perforations. Myringoplasty was performed through postauricular approach by underlay graft using conchal perichondrial graft. Patients were classified into two groups: case group included 32 patients who had undergone myringoplasty with use of autologous PRP and control group included 32 patients who had undergone myringoplasty without use of autologous PRP. Both groups were statistically matched with regard to age and sex. At 6 months postoperatively, success rate (graft taking) in case group (100%) was significantly higher than in control group (81.25%) (P=0.02). Success in terms of hearing gain (≥10dB) was achieved in 21 patients (65.6%) in case group and 11 patients (34.4%) in control group with statistically non-significant difference (P=0.079). Infection rate in control group (12.5%) was found to be significantly higher than in case group (P<0.0001). Topical autologous PRP application during myringoplasty is safe and highly efficient and successful with no reported complication. PRP not only enhances healing...Continue Reading

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Citations

Apr 15, 2016·The Laryngoscope·Mohammad Waheed El-AnwarAmal Saeed Quriba
Jul 25, 2018·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·Mahmoud Fawzy MandourMohamed Fathy Khalil
Jun 20, 2020·Indian Journal of Otolaryngology and Head and Neck Surgery : Official Publication of the Association of Otolaryngologists of India·M K Taneja
Jun 2, 2020·European Archives of Oto-rhino-laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery·Serap Sahin OnderMustafa Salih Canpolat
Aug 29, 2017·Ear, Nose, & Throat Journal·Mohammad Waheed El-AnwarYaser Ahmad Foad
Nov 22, 2019·Indian Journal of Otolaryngology and Head and Neck Surgery : Official Publication of the Association of Otolaryngologists of India·Rajendran Dinesh Kumar

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