Topographic correlation between juxtapapillary choroidal thickness and parapapillary deep-layer microvasculature dropout in primary open-angle glaucoma

The British Journal of Ophthalmology
Seung Hyen LeeTae-Woo Kim

Abstract

To investigate the topographic relationship between parapapillary deep-layer microvasculature dropout (MvD) as assessed by optical coherence tomography (OCT) angiography (OCTA) and the juxtapapillary choroidal thickness (JPCT) in primary open-angle glaucoma (POAG). A total of 194 eyes (138 POAG and 56 control eyes) having parapapillary atrophy (PPA) were imaged using the swept-source OCT and OCTA to examine the microstructure of PPA and measure the JPCT, and to determine the presence of the MvD. MvD was defined as a focal sectoral capillary dropout without any visible microvascular network identified in the parapapillary deep-layer in the en face OCTA images. JPCT was smaller in the POAG group than control group at 6-, 6.5-, 7- and 7.5-o'clock meridians (all p≤0.002). When POAG eyes were classified into those with parapapillary γ-zone and those with only β-zone without γ-zone, the mean JPCT was significantly smaller in the latter (p=0.027). The JPCT differed between with and without MvD only in eyes with a γ-zone: the JPCT was smaller in the eyes having MvD at 7- and 7.5-o'clock meridians (both p=0.001), where MvD was detected most frequently. However, such a difference was not observed in the eyes with only β-zone without the ...Continue Reading

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Jun 12, 2016·Acta Ophthalmologica·Kyoung Min LeeTae-Woo Kim

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Citations

Jul 20, 2018·Investigative Ophthalmology & Visual Science·Qi ZhangJost B Jonas
Jun 17, 2020·Investigative Ophthalmology & Visual Science·Seung Hyen LeeTae-Woo Kim
Dec 20, 2018·Biomedical Papers of the Medical Faculty of the University Palacký, Olomouc, Czechoslovakia·Gaile GudauskieneDalia Zaliuniene
Mar 3, 2020·Acta Ophthalmologica·Gyu-Nam KimTae-Woo Kim
Jul 22, 2018·Investigative Ophthalmology & Visual Science·Jun Woo ParkNeha Khandelwal
Mar 6, 2019·Investigative Ophthalmology & Visual Science·Youn Hye JoMichael S Kook
Jan 3, 2020·International Ophthalmology·Xiujuan GuoYanhao Li
Mar 17, 2020·Investigative Ophthalmology & Visual Science·Hae Rang KimMin Hee Suh

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